Protein Overview: FBpp0305074, FBp...

General Information:
Name(s) found:	FBpp0305074 [FlyBase] FBpp0305073 [FlyBase] FBpp0297199 [FlyBase] ari-1-PC / FBpp0089023 [FlyBase] ari-1-PB / FBpp0088500 [FlyBase] ari-1-PA / FBpp0088499 [FlyBase]
Description(s) found: Found 69 descriptions. SHOW ALL	type=protein; loc=X:complement(18026829..18026910,18026993..18027219,18027281..18027404,18027744..18028393,18029102..18029158,18029220..18029372,18030475..18030693); ID=FBpp0305074; name=ari-1-PF; parent=FBgn0017418,FBtr0332851; dbxref=REFSEQ:NP_001259672,GB_protein:AGB95514,FlyBase:FBpp0305074,FlyBase_Annotation_IDs:CG5659-PF; MD5=80d72af78f6af31f0eecce18649954ef; length=503; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=X:complement(18026829..18026910,18026993..18027219,18027281..18027404,18027744..18028393,18029102..18029158,18029220..18029372,18030475..18030693); ID=FBpp0305073; name=ari-1-PE; parent=FBgn0017418,FBtr0332850; dbxref=REFSEQ:NP_001259671,GB_protein:AGB95513,FlyBase:FBpp0305073,FlyBase_Annotation_IDs:CG5659-PE; MD5=80d72af78f6af31f0eecce18649954ef; length=503; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=X:complement(18026829..18026910,18026993..18027219,18027281..18027404,18027744..18028393,18029102..18029158,18029220..18029372,18030475..18030693); ID=FBpp0297199; name=ari-1-PD; parent=FBgn0017418,FBtr0306057; dbxref=REFSEQ:NP_001245736,GB_protein:AFH07449,FlyBase:FBpp0297199,FlyBase_Annotation_IDs:CG5659-PD; MD5=80d72af78f6af31f0eecce18649954ef; length=503; release=r5.56; species=Dmel; [FlyBase] The gene ariadne is referred to in FlyBase by the symbol Dmel\ari-1 (CG5659, FBgn0017418). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18026169..18031682. It has the cytological map location 16F7. It is reported to have molecular function</span>: ubiquitin-protein ligase activity. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic extracoxal depressor muscle 66; germline cyst; thoracico-abdominal ganglion; ovariole; optic neuropil; macrochaeta; coxal tergal remotor muscle; adult brain; cervical connective. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene ariadne is referred to in FlyBase by the symbol Dmel\ari-1 (CG5659, FBgn0017418). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18026169..18031682. It has the cytological map location 16F7. It is reported to have molecular function</span>: ubiquitin-protein ligase activity. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic extracoxal depressor muscle 66; germline cyst; thoracico-abdominal ganglion; ovariole; optic neuropil; macrochaeta; coxal tergal remotor muscle; adult brain; cervical connective. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene ariadne is referred to in FlyBase by the symbol Dmel\ari-1 (CG5659, FBgn0017418). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18026169..18031682. It has the cytological map location 16F7. It is reported to have molecular function</span>: ubiquitin-protein ligase activity. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic extracoxal depressor muscle 66; germline cyst; thoracico-abdominal ganglion; ovariole; optic neuropil; macrochaeta; coxal tergal remotor muscle; adult brain; cervical connective. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	503 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [NAS]
Biological Process:	NONE FOUND
Molecular Function:	ubiquitin-protein ligase activity [NAS] zinc ion binding [IEA] protein binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSDNDNDFC DNVDSGNVSS GDDGDDDFGM EVDLPSSADR QMDQDDYQYK VLTTDEIVQH  60
   61 QREIIDEANL LLKLPTPTTR ILLNHFKWDK EKLLEKYFDD NTDEFFKCAH VINPFNATEA 120
  121 IKQKTSRSQC EECEICFSQL PPDSMAGLEC GHRFCMPCWH EYLSTKIVAE GLGQTISCAA 180
  181 HGCDILVDDV TVANLVTDAR VRVKYQQLIT NSFVECNQLL RWCPSVDCTY AVKVPYAEPR 240
  241 RVHCKCGHVF CFACGENWHD PVKCRWLKKW IKKCDDDSET SNWIAANTKE CPRCSVTIEK 300
  301 DGGCNHMVCK NQNCKNEFCW VCLGSWEPHG SSWYNCNRYD EDEAKTARDA QEKLRSSLAR 360
  361 YLHYYNRYMN HMQSMKFENK LYASVKQKME EMQQHNMSWI EVQFLKKAVD ILCQCRQTLM 420
  421 YTYVFAYYLK KNNQSMIFED NQKDLESATE MLSEYLERDI TSENLADIKQ KVQDKYRYCE 480
  481 KRCSVLLKHV HEGYDKEWWE YTE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
ubiquitin-protein ligase activity	5.25982737281228	bayes_pls_golite062009
small conjugating protein ligase activity	5.16068345159314	bayes_pls_golite062009
acid-amino acid ligase activity	4.24782814163304	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	2.79292110382407	bayes_pls_golite062009
binding	2.70912934275371	bayes_pls_golite062009
protein binding	1.48593945455888	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.02238152139385	bayes_pls_golite062009
transcription regulator activity	0.911827807813353	bayes_pls_golite062009
ubiquitin-specific protease activity	0.821040441472875	bayes_pls_golite062009
transcription factor binding	0.769719546176331	bayes_pls_golite062009
nucleic acid binding	0.69956438716198	bayes_pls_golite062009
transcription repressor activity	0.451160479135532	bayes_pls_golite062009
ligase activity	0.424146907469434	bayes_pls_golite062009
DNA binding	0.369510087469936	bayes_pls_golite062009
cysteine-type peptidase activity	0.356312424125648	bayes_pls_golite062009
hydrolase activity	0.185228576891116	bayes_pls_golite062009
catalytic activity	0.168711389690753	bayes_pls_golite062009
peptidase activity	0.107857202210184	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.0136579100966835	bayes_pls_golite062009

Term	Confidence	Notes
ubiquitin-protein ligase activity	5.65442784325159	bayes_pls_golite062009
small conjugating protein ligase activity	5.55686022186257	bayes_pls_golite062009
acid-amino acid ligase activity	4.59153177011595	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	3.07217714843839	bayes_pls_golite062009
binding	2.78710909602478	bayes_pls_golite062009
protein binding	1.5975811408548	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.2126425713931	bayes_pls_golite062009
ubiquitin-specific protease activity	1.03469202541773	bayes_pls_golite062009
transcription regulator activity	0.943706743211193	bayes_pls_golite062009
transcription factor binding	0.90065892745057	bayes_pls_golite062009
nucleic acid binding	0.708499177773075	bayes_pls_golite062009
ligase activity	0.63517530468004	bayes_pls_golite062009
transcription repressor activity	0.517687629465752	bayes_pls_golite062009
cysteine-type peptidase activity	0.50197530717959	bayes_pls_golite062009
DNA binding	0.365874679056682	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.265769062717221	bayes_pls_golite062009
hydrolase activity	0.156835837705934	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009
peptidase activity	0.121357659741468	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..114]	MSA	3.376994	View MSA. No confident structure predictions are available.
2	View Details	[115..187]	PSI-BLAST	3.39794	Solution Structure of the RING domain of the Tripartite motif protein 32
3	View Details	[188..291]	FFAS03	3.4	Solution Structure of the IBR domain of the RING finger protein 31 protein
4	View Details	[292..343]	PSI-BLAST	8.221849	Solution Structure of the C-terminal RING from a RING-IBR-RING (TRIAD) motif
5	View Details	[344..503]	MSA	7.302997	View MSA. No confident structure predictions are available.

Protein Overview: FBpp0305074, FBp...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: