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Protein Overview: FBpp0311925, CG1...

General Information:
Name(s) found: FBpp0311925 [FlyBase]
CG10992-PA / FBpp0073669 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • type=protein; loc=X:complement(13674210..13674683,13675192..13675359,13675506..13675766,13675843..13675962); ID=FBpp0311925; name=CtsB1-PC; parent=FBgn0030521,FBtr0346091; dbxref=FlyBase:FBpp0311925,FlyBase_Annotation_IDs:CG10992-PC; MD5=c0e863d5d7e8fef2dffe44515c777e07; length=340; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG10992 (CG10992, FBgn0030521). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13674051..13676214. It has the cytological map location 12C4. Based on sequence similarity, it is predicted to have molecular function</span>: cysteine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 340 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: autophagic cell death [IEP]
    regulation of catalytic activity [IEA]
    proteolysis [IEA]
    salivary gland cell autophagic cell death [IEP]
    Molecular Function: cysteine-type endopeptidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLLLLVATA ASVAALTSGE PSLLSDEFIE VVRSKAKTWT VGRNFDASVT EGHIRRLMGV  60
   61 HPDAHKFALP DKREVLGDLY VNSVDELPEE FDSRKQWPNC PTIGEIRDQG SCGSCWAFGA 120
  121 VEAMSDRVCI HSGGKVNFHF SADDLVSCCH TCGFGCNGGF PGAAWSYWTR KGIVSGGPYG 180
  181 SNQGCRPYEI SPCEHHVNGT RPPCAHGGRT PKCSHVCQSG YTVDYAKDKH FGSKSYSVRR 240
  241 NVREIQEEIM TNGPVEGAFT VYEDLILYKD GVYQHEHGKE LGGHAIRILG WGVWGEEKIP 300
  301 YWLIGNSWNT DWGDHGFFRI LRGQDHCGIE SSISAGLPKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..340] PSI-BLAST 76.30103 CRYSTAL STRUCTURE OF HUMAN RECOMBINANT PROCATHEPSIN B AT 3.2 ANGSTROM RESOLUTION

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  4.90619850296986 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.64381885397949 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.75054525912786 bayes_pls_golite062009
  • hydrolase activity
    		•  3.74079711298952 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.71117522993364 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.95802900199539 bayes_pls_golite062009
  • binding
    		•  1.49113376575534 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • protein binding
    		•  0.874003454509364 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.649171767629235 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  0.59115205419466 bayes_pls_golite062009
  • kininogen binding
    		•  0.41283715939055 bayes_pls_golite062009
  • signal transducer activity
    		•  0.26868506520228 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.26868506520228 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.0101379718864654 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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