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Protein Overview: Cyp4g15-PA, FBpp...

General Information:
Name(s) found: FBpp0312025 [FlyBase]
Cyp4g15-PA / FBpp0073352 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • type=protein; loc=X:join(11371626..11371824,11372417..11372614,11373047..11373229,11375558..11376246,11376343..11376634,11376731..11376894); ID=FBpp0312025; name=Cyp4g15-PC; parent=FBgn0030304,FBtr0346268; dbxref=FlyBase:FBpp0312025,FlyBase_Annotation_IDs:CG11715-PC; MD5=38cfe6fdd8b2acc4b432ed5b59ef087b; length=574; release=r5.56; species=Dmel; [FlyBase]
  • The gene Cyp4g15 is referred to in FlyBase by the symbol Dmel\Cyp4g15 (CG11715, FBgn0030304). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11371114..11377138. It has the cytological map location 10B15. Based on sequence similarity, it is predicted to have molecular function</span>: electron carrier activity. It is reported to be involved in the biological process</span>: steroid biosynthetic process. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 574 amino acids

    Gene Ontology:
    Cellular Component: membrane [NAS]
    microsome [NAS]
    Biological Process: oxidation reduction [IEA]
    steroid biosynthetic process [NAS]
    Molecular Function: electron carrier activity [IEA][ISS][NAS]
    monooxygenase activity [IEA]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVLKKDAAL GSPSSVFYFL LLPTLVLWYI YWRLSRAHLY RLAGRLPGPR GLPIVGHLFD  60
   61 VIGPASSVFR TVIRKSAPFE HIAKMWIGPK LVVFIYDPRD VELLLSSHVY IDKASEYKFF 120
  121 KPWLGDGLLI STGQKWRSHR KLIAPTFHLN VLKSFIELFN ENSRNVVRKL RAEDGRTFDC 180
  181 HDYMSEATVE ILLETAMGVS KKTQDKSGFE YAMAVMRMCD ILHARHRSIF LRNEFVFTLT 240
  241 RYYKEQGRLL NIIHGLTTKV IRSKKAAFEQ GTRGSLAQCE LKAAALERER EQNGGVDQTP 300
  301 STAGSDEKDR EKDKEKASPV AGLSYGQSAG LKDDLDVEDN DIGEKKRLAF LDLMLESAQN 360
  361 GALITDTEIK EQVDTIMFEG HDTTAAGSSF FLSLMGIHQD IQDRVLAELD SIFGDSQRPA 420
  421 TFQDTLEMKY LERCLMETLR MYPPVPLIAR ELQEDLKLNS GNYVIPRGAT VTVATVLLHR 480
  481 NPKVYANPNV FDPDNFLPER QANRHYYAFV PFSAGPRSCV GRKYAMLKLK ILLSTILRNY 540
  541 RVYSDLTESD FKLQADIILK REEGFRVRLQ PRTS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..574] PSI-BLAST 77.09691 Crystal Structure of Human Microsomal P450 3A4

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  6.3313834755701 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.24344797738248 bayes_pls_golite062009
  • demethylase activity
    		•  2.80780658333504 bayes_pls_golite062009
  • oxygen binding
    		•  2.77495508953933 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  2.36480328243514 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.33937429425924 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  2.0071742914584 bayes_pls_golite062009
  • retinoid binding
    		•  1.84712870343774 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.72341042419615 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  1.46109575978397 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  1.20113920678403 bayes_pls_golite062009
  • binding
    		•  1.0881336564542 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  0.88385909514903 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  0.38659560844654 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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