Protein Overview: Klp10A-PB, Klp10...

General Information:
Name(s) found:	FBpp0312027 [FlyBase] Klp10A-PC / FBpp0073335 [FlyBase] Klp10A-PB / FBpp0073334 [FlyBase] Klp10A-PD / FBpp0073333 [FlyBase] Klp10A-PE / FBpp0073332 [FlyBase] Klp10A-PA / FBpp0073331 [FlyBase]
Description(s) found: Found 81 descriptions. SHOW ALL	type=protein; loc=X:complement(11025013..11025333,11026584..11027396,11027473..11027719,11028913..11029949); ID=FBpp0312027; name=Klp10A-PF; parent=FBgn0030268,FBtr0346270; dbxref=FlyBase:FBpp0312027,FlyBase_Annotation_IDs:CG1453-PF; MD5=d1d9bec51d6bfdbe21d965ec065be72b; length=805; release=r5.56; species=Dmel; [FlyBase] The gene Klp10A is referred to in FlyBase by the symbol Dmel\Klp10A (CG1453, FBgn0030268). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11024269..11031056. It has the cytological map location 10A6. There is experimental evidence that it has the molecular function</span>: motor activity; SUMO binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization; spindle organization; mitotic anaphase A; mitotic sister chromatid segregation. 10 alleles are reported. The phenotypes of these alleles are annotated with: spindle microtubule; S2 cell-line; spindle pole; spindle; microtubule; astral microtubule. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene Klp10A is referred to in FlyBase by the symbol Dmel\Klp10A (CG1453, FBgn0030268). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11024269..11031056. It has the cytological map location 10A6. There is experimental evidence that it has the molecular function</span>: motor activity; SUMO binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization; spindle organization; mitotic anaphase A; mitotic sister chromatid segregation. 10 alleles are reported. The phenotypes of these alleles are annotated with: spindle microtubule; S2 cell-line; spindle pole; spindle; microtubule; astral microtubule. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene Klp10A is referred to in FlyBase by the symbol Dmel\Klp10A (CG1453, FBgn0030268). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11024269..11031056. It has the cytological map location 10A6. There is experimental evidence that it has the molecular function</span>: motor activity; SUMO binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization; spindle organization; mitotic anaphase A; mitotic sister chromatid segregation. 10 alleles are reported. The phenotypes of these alleles are annotated with: spindle microtubule; S2 cell-line; spindle pole; spindle; microtubule; astral microtubule. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene Klp10A is referred to in FlyBase by the symbol Dmel\Klp10A (CG1453, FBgn0030268). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11024269..11031056. It has the cytological map location 10A6. There is experimental evidence that it has the molecular function</span>: motor activity; SUMO binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization; spindle organization; mitotic anaphase A; mitotic sister chromatid segregation. 10 alleles are reported. The phenotypes of these alleles are annotated with: spindle microtubule; S2 cell-line; spindle pole; spindle; microtubule; astral microtubule. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene Klp10A is referred to in FlyBase by the symbol Dmel\Klp10A (CG1453, FBgn0030268). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11024269..11031056. It has the cytological map location 10A6. There is experimental evidence that it has the molecular function</span>: motor activity; SUMO binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization; spindle organization; mitotic anaphase A; mitotic sister chromatid segregation. 10 alleles are reported. The phenotypes of these alleles are annotated with: spindle microtubule; S2 cell-line; spindle pole; spindle; microtubule; astral microtubule. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	805 amino acids
Gene Ontology:
Cellular Component:	kinetochore microtubule [IDA] spindle pole [IDA] kinesin complex [ISS]
Biological Process:	spindle organization [IMP] mitotic spindle organization [IMP] mitotic sister chromatid segregation [IMP] mitotic anaphase A [IDA] microtubule-based movement [IEA]
Molecular Function:	ATP binding [IEA] SUMO binding [IPI] microtubule motor activity [IEA] motor activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDMITVGQSV KIKRTDGRVH MAVVAVINQS GKCITVEWYE RGETKGKEVE LDAILTLNPE  60
   61 LMQDTVEQHA APEPKKQATA PMNLSRNPTQ SAIGGNLTSR MTMAGNMLNK IQESQSIPNP 120
  121 IVSSNSVNTN SNSNTTAGGG GGTTTSTTTG LQRPRYSQAA TGQQQTRIAS AVPNNTLPNP 180
  181 SAAASAGPAA QGVATAATTQ GAGGASTRRS HALKEVERLK ENREKRRARQ AEMKEEKVAL 240
  241 MNQDPGNPNW ETAQMIREYQ STLEFVPLLD GQAVDDHQIT VCVRKRPISR KEVNRKEIDV 300
  301 ISVPRKDMLI VHEPRSKVDL TKFLENHKFR FDYAFNDTCD NAMVYKYTAK PLVKTIFEGG 360
  361 MATCFAYGQT GSGKTHTMGG EFNGKVQDCK NGIYAMAAKD VFVTLNMPRY RAMNLVVSAS 420
  421 FFEIYSGKVF DLLSDKQKLR VLEDGKQQVQ VVGLTEKVVD GVEEVLKLIQ HGNAARTSGQ 480
  481 TSANSNSSRS HAVFQIVLRP QGSTKIHGKF SFIDLAGNER GVDTSSADRQ TRMEGAEINK 540
  541 SLLALKECIR ALGKQSAHLP FRVSKLTQVL RDSFIGEKSK TCMIAMISPG LSSCEHTLNT 600
  601 LRYADRVKEL VVKDIVEVCP GGDTEPIEIT DDEEEEELNM VHPHSHQLHP NSHAPASQSN 660
  661 NQRAPASHHS GAVIHNNNNN NNKNGNAGNM DLAMLSSLSE HEMSDELIVQ HQAIDDLQQT 720
  721 EEMVVEYHRT VNATLETFLA ESKALYNLTN YVDYDQDSYC KRGESMFSQL LDIAIQCRDM 780
  781 MAEYRAKLAK EEMLSCSFNS PNGKR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..78]	FFAS03	0.954	No description for 2d9tA was found.
2	View Details	[79..174]	deduced	N/A	No confident structure predictions are available.
3	View Details	[175..603]	PSI-BLAST	101.0	No description for 2gryA was found.
4	View Details	[604..805]	PSI-BLAST	7.0	Heavy meromyosin subfragment

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: Klp10A-PB, Klp10...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: