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Protein Overview: Nf-YC-PA

General Information:
Name(s) found: Nf-YC-PA / FBpp0070935 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Nuclear factor Y-box C is referred to in FlyBase by the symbol Dmel\Nf-YC (CG3075, FBgn0029905). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6712208..6714948. It has the cytological map location 6D3. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of smoothened signaling pathway; axon guidance; cellular process; wing disc pattern formation. 14 alleles are reported. The phenotypes of these alleles are annotated with: wing; lamina. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 601 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: wing disc pattern formation [IMP]
    axon guidance [IMP]
    cellular process [IMP]
    regulation of smoothened signaling pathway [IMP]
    Molecular Function: transcription factor activity [ISS]
    sequence-specific DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYATNNGGTN KAPNSNATSM FDNTITVTPI KMELGQAYAK SQNSAAMQRR TPNAVVVTSS  60
   61 STVSSAQQQQ QQQGQQQQQT VPMASLVSNA CTLVNPSMSV TVATTVASGA KEKTTKATRT 120
  121 QVARKPPPTI DNFWPNIVSE VHSIGQVDAK HQVLPLARIK KIMKLDENAK MIAGEAPLLF 180
  181 AKACEYFIQE LTMHAWVHTE ESRRRTLQRS DIAQAIANYD QFDFLIDIVP REEIKPSSAQ 240
  241 KTKDGSTSSS SGMAGAASSA ASTSNTATSN AAASVAGNAT ATGNFVASGS TVPATTAGGL 300
  301 KLDTTGATNA AEVLGFSTVN SDIFSAQLQQ QQQQQQQHAA QQQQQQQQQQ HHQAHPQQVQ 360
  361 IIQQGAGGQQ LQYFIALPSQ QAAQLVQQPQ PAQNHLPINI LSTQQPTQQL ILTAGPNGQL 420
  421 TATPAPQTTA QQQTALLQNL AQQQQQHQQH QQQIQLLQQV VTPTGELTNV PIAINASHLN 480
  481 LLQRLQMQQQ QQQQQQQQQQ QQQQQQVIIP TQLLTTQQLL QLGGAPTVAH QQQQQQQQHA 540
  541 NLTQQSNASA VASGTPIFIN STMTGAQAAA TQAQQQQSAQ QQQAQTISTM STDRTLTGGF 600
  601 R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..234] PSI-BLAST 35.045757 Nuclear transcription factor Y subunit gamma (Nf-Yc2)
    2 View Details [235..304] deduced N/A No confident structure predictions are available.
    3 View Details [305..523] PSI-BLAST 7.045757 Sec24
    4 View Details [524..601] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.27510691458843 bayes_pls_golite062009
  • DNA binding
    		•  2.84801656088633 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.61296736453579 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.30478015157761 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.18120033767195 bayes_pls_golite062009
  • protein binding
    		•  1.07873333188144 bayes_pls_golite062009
  • transcription factor activity
    		•  1.01889555697279 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.378390077792097 bayes_pls_golite062009
  • transcription factor binding
    		•  0.20278000165075 bayes_pls_golite062009
  • transcription activator activity
    		•  0.16305156761639 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.0427278296123499 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle