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Any process that activates or increases the frequency, rate or extent of smoothened signaling. Any process that modulates the frequency, rate or extent of a signaling pathway. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any process that modulates the frequency, rate or extent of smoothened signaling. Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of smoothened signaling pathway
Acc: GO:0008589
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of smoothened signaling.
Synonyms:
  • GO:0043109
  • regulation of smoothened receptor activity by patched
  • regulation of smoothened by patched
  • regulation of hedgehog signaling pathway
  • regulation of smoothened signalling pathway
  • regulation of smoothened activity
  • regulation of hh signaling pathway
  • GO:0007226
Proteins in PDR annotated with:
   This term: 37 [Search]
   Term or descendants: 84 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008589 - regulation of smoothened signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle