Protein Overview: br-PI, br-PH, br...

General Information:
Name(s) found:	FBpp0304572 [FlyBase] br-PI / FBpp0289657 [FlyBase] br-PH / FBpp0289656 [FlyBase] br-PB / FBpp0070253 [FlyBase] br-PC / FBpp0070251 [FlyBase]
Description(s) found: Found 66 descriptions. SHOW ALL	type=protein; loc=X:join(1518555..1518740,1529865..1530053,1530129..1530582,1530672..1530945,1531033..1531172,1531317..1531367,1541398..1542746); ID=FBpp0304572; name=br-PQ; parent=FBgn0000210,FBtr0332293; dbxref=REFSEQ:NP_001259134,GB_protein:AGB94980,FlyBase:FBpp0304572,FlyBase_Annotation_IDs:CG11491-PQ; MD5=4da494ae6e11d6587db7ed748fc55f4c; length=880; release=r5.56; species=Dmel; [FlyBase] The gene broad is referred to in FlyBase by the symbol Dmel\br (CG11491, FBgn0000210). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1503176..1553962. It has the cytological map location 2B3-2B4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity; DNA binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; sensory organ development; reproductive process in a multicellular organism; catabolic process; eclosion; response to symbiont; compound eye development; response to hormone stimulus; gland morphogenesis. 140 alleles are reported. The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; nervous system; peripheral nervous system; external compound sense organ; adult brain; multi-cell-component structure; egg; mouthpart. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase] The gene broad is referred to in FlyBase by the symbol Dmel\br (CG11491, FBgn0000210). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1503176..1553962. It has the cytological map location 2B3-2B4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity; DNA binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; sensory organ development; reproductive process in a multicellular organism; catabolic process; eclosion; response to symbiont; compound eye development; response to hormone stimulus; gland morphogenesis. 140 alleles are reported. The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; nervous system; peripheral nervous system; external compound sense organ; adult brain; multi-cell-component structure; egg; mouthpart. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase] The gene broad is referred to in FlyBase by the symbol Dmel\br (CG11491, FBgn0000210). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1503176..1553962. It has the cytological map location 2B3-2B4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity; DNA binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; sensory organ development; reproductive process in a multicellular organism; catabolic process; eclosion; response to symbiont; compound eye development; response to hormone stimulus; gland morphogenesis. 140 alleles are reported. The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; nervous system; peripheral nervous system; external compound sense organ; adult brain; multi-cell-component structure; egg; mouthpart. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase] The gene broad is referred to in FlyBase by the symbol Dmel\br (CG11491, FBgn0000210). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1503176..1553962. It has the cytological map location 2B3-2B4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity; DNA binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; sensory organ development; reproductive process in a multicellular organism; catabolic process; eclosion; response to symbiont; compound eye development; response to hormone stimulus; gland morphogenesis. 140 alleles are reported. The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; nervous system; peripheral nervous system; external compound sense organ; adult brain; multi-cell-component structure; egg; mouthpart. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	880 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] intracellular [IEA]
Biological Process:	male genitalia morphogenesis [IMP] regulation of development, heterochronic [IMP][TAS] response to ecdysone [IMP] regulation of transcription, DNA-dependent [NAS] salivary gland histolysis [IMP][NAS] salivary gland cell autophagic cell death [NAS] eclosion [IEP] metamorphosis [NAS][TAS] ecdysone-mediated induction of salivary gland cell autophagic cell death [NAS] larval central nervous system remodeling [IMP] progression of morphogenetic furrow during compound eye morphogenesis [IMP] muscle fiber development [IGI] response to symbiont [IMP] compound eye photoreceptor fate commitment [IMP] cell death [TAS] oogenesis [IMP] autophagy [IMP]
Molecular Function:	DNA binding [IDA] transcription factor activity [TAS] zinc ion binding [IEA] protein binding [IEA] specific RNA polymerase II transcription factor activity [NAS] specific transcriptional repressor activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDTQHFCLR WNNYQSSITS AFENLRDDEA FVDVTLACEG RSIKAHRVVL SACSPYFREL  60
   61 LKSTPCKHPV ILLQDVNFMD LHALVEFIYH GEVNVHQKSL QSFLKTAEVL RVSGLTQQQA 120
  121 EDTHSHLAQI QNLANSGGRT PLNTHTQSLP HPHHGSLHDD GGSSTLFSRQ GAGSPPPTAV 180
  181 PSLPSHINNQ LLKRMAMMHR SSAAAAAEET SHAFKRLRGS DNSLPLSGAV GSGSNNNSPD 240
  241 LPPLHARSAS PQQTPADFST IKHHNNNNTP PLKEEKRNGP TGNGNSGNGN GNGNGASNGN 300
  301 GISISDKLGS LTPSPLARAG ADDVKSEPMD MVCSNNNANA NDEHSNDSTG EHDANRSSSG 360
  361 DGGKGSLSSG NDEEIGDGLA SHHAAPQFIM SPAENKMFHA AAFNFPNIDP SALLGLNTQL 420
  421 QQSGDLAVSP QGGSTGSLLS GVIVPGGSGG TPSNSSSNNN NNNSNNQQQK VEQQSSPHQL 480
  481 LQQQHHSTPH TNSPQLKQEQ PKSGGGSCKS SDLHIAAGSE RSLSRSSQGM PDAGGHSATP 540
  541 SPTAAYHKRE RERERERERE RERERERSLD HERDLERPGG TGSPPPPPPS HHSHFGQHPL 600
  601 SLLPSHHQLH ATHHELSAAA AHHAHAHAHA AHAHALARAG SPMEHHHLLH HRRASLSPSG 660
  661 AVSSASGAGG RGGGAGGPGG PGGSLLSSVR AQDVAQANRL LLPLPLNACH RCDVCGKLLS 720
  721 TKLTLKRHKE QQHLQPLNNA VCNLCHKVFR TLNSLNNHKS IYHRRQKNHH SYFHHGAGVS 780
  781 QAGSPGSRLH QSLSSLSAAA AAANNSVNVG GGSVGGAGGN AVAAAAAAAA AAAELLLSPI 840
  841 VGAAAVAGGT ASSTLQLAAA HQQQQQQSSP GIVKPCMDFL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..149]	PSI-BLAST	34.522879	No description for 2nn2A was found.
2	View Details	[150..210]	deduced	N/A	No confident structure predictions are available.
3	View Details	[211..296]	deduced	N/A	No confident structure predictions are available.
4	View Details	[297..479]	deduced	N/A	No confident structure predictions are available.
5	View Details	[480..606]	deduced	N/A	No confident structure predictions are available.
6	View Details	[607..696]	PSI-BLAST	11.0	Transcription factor IIIA, TFIIIA
7	View Details	[697..880]	PSI-BLAST	40.045757	No description for 2i13A was found.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.35

Protein Overview: br-PI, br-PH, br...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: