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Protein Overview: krz-PA, FBpp0293792

General Information:
Name(s) found: FBpp0293792 [FlyBase]
krz-PA / FBpp0085236 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • type=protein; loc=3R:complement(27874750..27875591,27876991..27877561); ID=FBpp0293792; name=krz-PB; parent=FBgn0040206,FBtr0305268; dbxref=REFSEQ:NP_001247400,GB_protein:AFH06717,FlyBase:FBpp0293792,FlyBase_Annotation_IDs:CG1487-PB; MD5=8b75c5342ce88d4fa8229cc8ba1de16c; length=470; release=r5.56; species=Dmel; [FlyBase]
  • The gene kurtz is referred to in FlyBase by the symbol Dmel\krz (CG1487, FBgn0040206). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27873827..27877711. It has the cytological map location 100E3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: negative regulation of Notch signaling pathway; behavior. 15 alleles are reported. The phenotypes of these alleles are annotated with: lamellocyte; embryonic/larval fat body. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 470 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of Notch signaling pathway [IGI][IMP]
    behavior [IMP]
    sensory perception [IEA]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGGGGGSGG ANVSNGSSTN VTAAGSTGGG SAGDETGGDA SSRRQATRVF KKSSSNGKIT  60
   61 VYLGKRDFVD HVTHVDPIDG VVFIDPEYVK DRKVFGQVLA AFRYGREDLD VLGLTFRKDL 120
  121 YLAHEQIYPP MQLDRPMTRL QERLIKKLGP NAHPFYFEVP PYCPASVSLQ PAPGDVGKSC 180
  181 GVDYELKAFV GENVEDKPHK RNSVRLTIRK VMYAPSKVGE QPSIEVSKEF MMKPNKIHLE 240
  241 ATLDKELYHH GEKISVNVHV ANNSNRTVKK IKVCVRQFAD ICLFSTAQYK SVVAEIESED 300
  301 GCQVAPGFTL SKVFELCPLL ANNKDKWGLA LDGQLKHEDT NLASSTLITN PAQRESLGIM 360
  361 VHYKVKVKLL ISSPLLNGDL VAELPFTLMH PKPEEEEHPL LGERSPRASL AGGGLPLVSM 420
  421 SDGETESATG GQDVPTTTNL IQLDDDEAQD DDIIFEDFAR LRLKGAETEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..470] PSI-BLAST 129.0 Arrestin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • metarhodopsin binding
    		•  8.28769992538003 bayes_pls_golite062009
  • opsin binding
    		•  5.28980129610811 bayes_pls_golite062009
  • binding
    		•  2.01555579124143 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.93701073361946 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.63290276735956 bayes_pls_golite062009
  • actin binding
    		•  1.55497114340347 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  1.5302582659987 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  1.5302582659987 bayes_pls_golite062009
  • protein binding
    		•  1.50286160643298 bayes_pls_golite062009
  • gated channel activity
    		•  1.42896395862304 bayes_pls_golite062009
  • transporter activity
    		•  1.2104812424938 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.20869454170074 bayes_pls_golite062009
  • kinase activity
    		•  1.1759320472197 bayes_pls_golite062009
  • protein kinase activity
    		•  1.16294708854294 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07068941646158 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.03266511838083 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.929966017205863 bayes_pls_golite062009
  • potassium channel activity
    		•  0.871728492941793 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.848303301157398 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.829939555243379 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.829140804686535 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.820413268771765 bayes_pls_golite062009
  • channel activity
    		•  0.796075411518814 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.796075411518814 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.790863065462458 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.787347074261486 bayes_pls_golite062009
  • cation channel activity
    		•  0.770955130885998 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.760234877475175 bayes_pls_golite062009
  • ion channel activity
    		•  0.743051345681968 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.726369450752205 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.698762820554681 bayes_pls_golite062009
  • transferase activity
    		•  0.563590737734601 bayes_pls_golite062009
  • signal transducer activity
    		•  0.523284964365729 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.523284964365729 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  0.43450134854604 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle