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Protein Overview: Gfat2-PA

General Information:
Name(s) found: Gfat2-PA / FBpp0084666 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Glutamine:fructose-6-phosphate aminotransferase 2 is referred to in FlyBase by the symbol Dmel\Gfat2 (CG1345, FBgn0039580). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:24162741..24165490. It has the cytological map location 98C4. Based on sequence similarity, it is predicted to have molecular function</span>: glutamine-fructose-6-phosphate transaminase (isomerizing) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate biosynthetic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 683 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: carbohydrate biosynthetic process [IEA]
    Molecular Function: sugar binding [IEA]
    glutamine-fructose-6-phosphate transaminase (isomerizing) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIFAYLNY LTPKSRQEVL DLLLQGLKRL EYRGYDSTGI AIDALNSGEA QSIMLVKRTG  60
   61 KVKVLEDAVA EVCRGQDYSL PIDTHIGIAH TRWATHGVPS EVNSHPQRSD EDNSFVVVHN 120
  121 GIITNYKDVK TLLEKRGYVF ESDTDTEVIA KLVHHLWQQH PGYTFGELVE QAIQQLEGAF 180
  181 AIAFKSKHFP GECVASRRGS PLLVGIKAKT KLATDHIPIL YAKAHRPHGQ PQQQAYQLLP 240
  241 PGDCNAEFQP LERKEVEYFF ASDASAVIEH TNRVIYLEDD DVAAVKSDGT LSIHRLNKSS 300
  301 DDPHAREIIT LKMEIQQIMK GNYDYFMLKE IFEQPESVVN TMRGRMRFDT QTVVLGGIKE 360
  361 YIPEIKRCRR LMLIACGTSY HSAVATRQLL EELTELPVMV ELASDFLDRN TPIFRDDVCF 420
  421 FISQSGETAD TLMALRYCKQ RGALIVGVTN TVGSSICRES HCGVHINAGP EIGVASTKAY 480
  481 TSQFISLVMF ALVMSEDRLS LQQRRLEIID GLSQLDEHIR TVLKLNSQVQ QLAKELYEHK 540
  541 SLLIMGRGFN FATCLEGALK VKELTYMHSE GILAGELKHG PLALVDKEMP VLMIVLRDPV 600
  601 YTKCMNALQQ VTSRKGRPIL ICEEGDNETM SFSTRSLQIP RTVDCLQGVL TVIPLQLLSY 660
  661 HIAVLRGCDV DCPRNLAKSV TVE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..683] PSI-BLAST 167.0 "Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutamine-fructose-6-phosphate transaminase (isomerizing) activity
    		•  4.12465195642555 bayes_pls_golite062009
  • glucose-6-phosphate isomerase activity
    		•  2.74527495029339 bayes_pls_golite062009
  • D-sedoheptulose 7-phosphate isomerase activity
    		•  2.03357282678145 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  1.99606027864666 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting aldoses and ketoses
    		•  1.49939040101274 bayes_pls_golite062009
  • sugar binding
    		•  1.40175307923331 bayes_pls_golite062009
  • peptidase activity
    		•  1.34295853726897 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.16226272745141 bayes_pls_golite062009
  • isomerase activity
    		•  0.875614547872629 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.798789250029517 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.759765292911898 bayes_pls_golite062009
  • binding
    		•  0.541510243044181 bayes_pls_golite062009
  • transferase activity
    		•  0.526806728662348 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  0.329741341879618 bayes_pls_golite062009
  • transaminase activity
    		•  0.307877519336205 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.0870260775261698 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle