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Protein Overview: Tbp-1-PA

General Information:
Name(s) found: Tbp-1-PA / FBpp0083843 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene Tat-binding protein-1 is referred to in FlyBase by the symbol Dmel\Tbp-1 (CG10370, FBgn0028684). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19578600..19580345. It has the cytological map location 95B1. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: cellular process; proteolysis. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 428 amino acids

    Gene Ontology:
    Cellular Component: proteasome regulatory particle, base subcomplex [ISS][NAS]
    cytoplasm [IEA]
    proteasome regulatory particle [IDA][ISS]
    Biological Process: proteolysis [IDA][ISS]
    cellular process [IMP]
    Molecular Function: ATPase activity [ISS]
    ATP binding [IEA]
    endopeptidase activity [IDA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQTLEDKSI WEDGEESLGE EVMRMSTDEI VSRTRLMDNE IKIMKSEVIR ITHEIQAQNE  60
   61 KIKDNTEKIK VNKTLPYLVS NVIELLDVDP QEEEDDGSVT VLDNQRKGKC AVIKTSTRQA 120
  121 YFLPVIGLVD AEKLKPGDLV GVNKDSYLIL ETLPAEYDAR VKAMEVDERP TEQYSDIGGL 180
  181 DKQIQELIEA VVLPMTHKEK FKNLGIHPPK GVLLYGPPGT GKTLLARACA AQTKSTFLKL 240
  241 AGPQLVQMFI GDGAKLVRDA FALAKEKAPA IIFIDELDAI GTKRFDSEKA GDREVQRTML 300
  301 ELLNQLDGFS STADIKVIAA TNRVDILDPA LLRSGRLDRK IEFPHPNEEA RARIMQIHSR 360
  361 KMNVSNDVNF EELSRSTDDF NGAQCKAVCV EAGMIALRRS ANSVTHEDFM DAIMEVQAKK 420
  421 KANLNYYA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..428] PSI-BLAST 89.522879 VCP/p97


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle