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Protein Overview: Rpn9-PA, Rpn9-PB

General Information:
Name(s) found: Rpn9-PA / FBpp0083861 [FlyBase]
Rpn9-PB / FBpp0083860 [FlyBase]
Description(s) found:
Found 38 descriptions.
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  • The gene Rpn9 is referred to in FlyBase by the symbol Dmel\Rpn9 (CG10230, FBgn0028691). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19557225..19559184. It has the cytological map location 95B1. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of exit from mitosis; proteolysis. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Rpn9 is referred to in FlyBase by the symbol Dmel\Rpn9 (CG10230, FBgn0028691). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19557225..19559184. It has the cytological map location 95B1. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of exit from mitosis; proteolysis. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 382 amino acids

    Gene Ontology:
    Cellular Component: proteasome regulatory particle [IDA][ISS]
    proteasome regulatory particle, lid subcomplex [ISS][NAS]
    Biological Process: regulation of exit from mitosis [IMP]
    proteolysis [IDA][ISS]
    Molecular Function: endopeptidase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNPQPNVTA YLATQKKTTN KELAAEWTLI EELYNEKLWN ELTIKLVTFV RHESLQDETA  60
   61 LLQLYQNFLS TFETKINPYG LIQILEVVVD NIGDKKEAIE FLEKMKDKVK ICDEAVWYLQ 120
  121 VMQGNLYLSN LNDLNATKKI IEELRDVLEE AGNVTPVHGK YYMLASQYYR RVGKHSDYYR 180
  181 CGLQFLGCSM DEYPRDQWAQ QAFFLGLAAL LGDGVYNIGE LLAHPILESL KGTENEWLME 240
  241 LLKAFNTGDI NKFNDMKKIW SKIPDLAAQE VKLRQKISLL CLMEMTFKRS AIERAISFTD 300
  301 IAQETKLPAK EVELLIMKAL ALDLVRGEID QVAGVVNMSW VQPRVLNRSQ IVGMASTLDT 360
  361 WMGAITNMEK LMENRAAEIL TN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] MSA 8.324996 View MSA. No confident structure predictions are available.
    2 View Details [187..262] MSA 1.375996 View MSA. No confident structure predictions are available.
    3 View Details [263..382] PSI-BLAST 9.09691 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  3.77201910025409 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • DNA binding
    		•  3.44642410378325 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.38144578566524 bayes_pls_golite062009
  • transcription factor activity
    		•  2.83460075788873 bayes_pls_golite062009
  • hydrolase activity
    		•  2.30467124306022 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.08341148210578 bayes_pls_golite062009
  • transcription activator activity
    		•  1.98504395280033 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.46680509390433 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.16843113623321 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.42135864069093 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.136726704233672 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.118016217031359 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle