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Protein Overview: CG6015-PA

General Information:
Name(s) found: CG6015-PA / FBpp0083581 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6015 (CG6015, FBgn0038927). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17857872..17860116. It has the cytological map location 94A1. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 2 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord commissure; ventral nerve cord; embryonic peripheral nervous system; longitudinal connective. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 576 amino acids

    Gene Ontology:
    Cellular Component: catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    spliceosomal complex [ISS]
    Biological Process: nuclear mRNA splicing, via spliceosome [IC][ISS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGLQSYASS SDEESDHADA ATATTNSEPS APIPDHLLPV DKTHSLSKSI AVCAAPTVVP  60
   61 LGASAVPRTL DPTLKEVTYN PRYEEMYAPV KGPEHPDLTM QQRAPRNTLA GYVEKAHINA 120
  121 FEFENQRRTF HTYGYALDPS VDDQADGQSF VGDLQSAYDD NGKTVFEPPK AKKLRKQEKN 180
  181 DNPEDIEGFL GPWGKFENEV SVAKPNEQER AELDELLSKR HKRGRIPEDK PLEEKSTLHI 240
  241 KDAYDYQGRS YLHAPHDLGV NLRSNAPPTK CFLPKAHIHT WSGHNKGISS IRWFPKTAHL 300
  301 LLSGSMDCRV KLWEVYGERR CIRTFSGHRQ AIKDIAWNNR GTNFLSASYD RYIKLWDAET 360
  361 GDVVSRFTTR KMPFCVKFHP DNSKQHLFVA GTSDKKIICW DTRSGDIVQE YDRHLGSVST 420
  421 ITFVDDNRRF VTTSDDKSMR IWEWDIPVDM KYIADPTMHS MPAVTLAPNG KWMACQSLDN 480
  481 KIVIFSALNR FKMNRKKTFT GHMVSGYACQ LDFSPDMSYL VSGDGDGKCY IWDWKTTKMY 540
  541 KKWQAHDGVC ISALWHPHEA SKVVTAGWDG QIKYWD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77] MSA 1.217994 View MSA. No confident structure predictions are available.
    2 View Details [78..133] deduced N/A No confident structure predictions are available.
    3 View Details [134..488] PSI-BLAST 78.045757 PAF-AH Holoenzyme: Lis1/Alfa2
    4 View Details [489..576] PSI-BLAST 79.0 No description for 2gnqA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
    		• 6.67009948605948 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
    		•  4.71992275913384 bayes_pls_golite062009
  • actin binding
    		•  3.86142918698875 bayes_pls_golite062009
  • RNA binding
    		•  3.77273677738815 bayes_pls_golite062009
  • snoRNA binding
    		•  3.28507672512266 bayes_pls_golite062009
  • GTPase activity
    		•  3.23750443966606 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • dynein binding
    		•  2.54821997913979 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.18628561734369 bayes_pls_golite062009
  • actin filament binding
    		•  2.0735069176589 bayes_pls_golite062009
  • dynactin binding
    		•  1.99805820148456 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.85632145559025 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.53722103498827 bayes_pls_golite062009
  • structural molecule activity
    		•  1.47097979074281 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  1.35170368882651 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.2886835964948 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.25687092973217 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  1.11754260203517 bayes_pls_golite062009
  • mRNA binding
    		•  1.05053985350578 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.01166033978052 bayes_pls_golite062009
  • myosin binding
    		•  0.989691178611801 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.702111212042669 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.625780732991652 bayes_pls_golite062009
  • DNA binding
    		•  0.561578774129549 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.443846546939402 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.428715007921149 bayes_pls_golite062009
  • transcription factor activity
    		•  0.243992994917491 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  0.231534552000461 bayes_pls_golite062009
  • protein kinase activity
    		•  0.229242350006544 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.220747580531792 bayes_pls_golite062009
  • ligase activity
    		•  0.20682813699621 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.157016319695991 bayes_pls_golite062009
  • myosin II binding
    		•  0.12060669039328 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • receptor binding
    		•  0.0390635451962911 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.00335766408304172 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle