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A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs. A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs. A macromolecular complex containing both protein and RNA molecules. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. Any of a series of ribonucleoprotein complexes that contain RNA and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the splicing of a messenger RNA primary transcript to excise an intron. A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: catalytic step 2 spliceosome
Acc: GO:0071013
Aspect: Cellular Component
Desc: A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
Synonyms:
  • mammalian spliceosomal complex C
  • mammalian spliceosomal complex C1
  • yeast spliceosomal complex A2-2
Proteins in PDR annotated with:
   This term: 186 [Search]
   Term or descendants: 191 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0071013 - catalytic step 2 spliceosome (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle