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Protein Overview: CG11453-PA

General Information:
Name(s) found: CG11453-PA / FBpp0083205 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG11453 (CG11453, FBgn0038734). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15609245..15611252. It has the cytological map location 92B2. Based on sequence similarity, it is predicted to have molecular function</span>: 4-coumarate-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 539 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEA]
    Molecular Function: 4-coumarate-CoA ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRSTTQFDK YTKIWSGPRP ASFFDADCSI GKILFAFMRN HPNSICQISD TEGTALTNGE  60
   61 AITFAIRIAQ QLKAMGLKQD DVVGIVGTNT TYLMPVVLGC LLNGTPFHAV SPWQDEDTIK 120
  121 HLFSITRPKL IFCDGKCFQR LSIIARILKS HVYTLKDHRL GMPRVEDLLE PTTAELYYVP 180
  181 ETLLLGGDHT VAILCTSGTT GLPKAVCISN SACLFDFGFV TGQDVLLSFS TIDWSAGMFN 240
  241 MLFSCCHGST RIITDRPYTP EYMIQLVEKY KVTLLTVVPQ QVASLLKTPT LNKQRLASIR 300
  301 FVSVGGGSCY VANLLKLQEF LITGQISYGY ALTECGGVAA NMGVAKPSSV GRIVPGVRVK 360
  361 ILDEAGRSLG HGETGEILVH NGKVWNGYYA NPNESKRMQD YQGWFHTGDM GYFDNENYLH 420
  421 IVERKEDLLR FHGAQYSPQE IEQVIAELPD VIEACVFGLW NEVDGDPAAA AVVKIPGSRL 480
  481 TEMDIVEYVA KRLVVDHKQL HCGVFFLPEL PKTGSGKVLR QQARDQALGK KWADHGNGH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..539] PSI-BLAST 106.0 FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-sulfur bonds
    		•  5.10123876514454 bayes_pls_golite062009
  • fatty acid ligase activity
    		•  4.83067429373059 bayes_pls_golite062009
  • long-chain fatty acid-CoA ligase activity
    		•  4.72692389032116 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  4.28278725989432 bayes_pls_golite062009
  • CoA-ligase activity
    		•  4.12850865352867 bayes_pls_golite062009
  • acetate-CoA ligase activity
    		•  3.83959707137518 bayes_pls_golite062009
  • Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
    		•  2.74744781333102 bayes_pls_golite062009
  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
    		•  2.74744781333102 bayes_pls_golite062009
  • luciferin monooxygenase activity
    		•  2.67396462766343 bayes_pls_golite062009
  • lipid transporter activity
    		•  2.59608399999188 bayes_pls_golite062009
  • ligase activity
    		•  2.49556073715112 bayes_pls_golite062009
  • fatty acid transporter activity
    		•  2.19262381655601 bayes_pls_golite062009
  • long-chain fatty acid transporter activity
    		•  1.91632961501352 bayes_pls_golite062009
  • catalytic activity
    		•  1.83545185797733 bayes_pls_golite062009
  • transporter activity
    		•  1.29780964436121 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07143339827205 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.03753946113449 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.54797726647835 bayes_pls_golite062009
  • binding
    		•  0.509078620937952 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.464663038956639 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.251681382273558 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.225448500718996 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.216579620878492 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.177812048124158 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.174283007890308 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.173963339749644 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0401881910649647 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0047964784091391 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle