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View Structure Prediction Details

Protein: CG11453-PA
Organism: Drosophila melanogaster
Length: 539 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11453-PA.

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
532.0 [0..7] [532..6]

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Predicted Domain #1
Region A:
Residues: [1-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRSTTQFDK YTKIWSGPRP ASFFDADCSI GKILFAFMRN HPNSICQISD TEGTALTNGE  60
   61 AITFAIRIAQ QLKAMGLKQD DVVGIVGTNT TYLMPVVLGC LLNGTPFHAV SPWQDEDTIK 120
  121 HLFSITRPKL IFCDGKCFQR LSIIARILKS HVYTLKDHRL GMPRVEDLLE PTTAELYYVP 180
  181 ETLLLGGDHT VAILCTSGTT GLPKAVCISN SACLFDFGFV TGQDVLLSFS TIDWSAGMFN 240
  241 MLFSCCHGST RIITDRPYTP EYMIQLVEKY KVTLLTVVPQ QVASLLKTPT LNKQRLASIR 300
  301 FVSVGGGSCY VANLLKLQEF LITGQISYGY ALTECGGVAA NMGVAKPSSV GRIVPGVRVK 360
  361 ILDEAGRSLG HGETGEILVH NGKVWNGYYA NPNESKRMQD YQGWFHTGDM GYFDNENYLH 420
  421 IVERKEDLLR FHGAQYSPQE IEQVIAELPD VIEACVFGLW NEVDGDPAAA AVVKIPGSRL 480
  481 TEMDIVEYVA KRLVVDHKQL HCGVFFLPEL PKTGSGKVLR QQARDQALGK KWADHGNGH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 106.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 5.10123876514454 bayes_pls_golite062009
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
acid-thiol ligase activity 4.28278725989432 bayes_pls_golite062009
CoA-ligase activity 4.12850865352867 bayes_pls_golite062009
acetate-CoA ligase activity 3.83959707137518 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
lipid transporter activity 2.59608399999188 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
fatty acid transporter activity 2.19262381655601 bayes_pls_golite062009
long-chain fatty acid transporter activity 1.91632961501352 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
transporter activity 1.29780964436121 bayes_pls_golite062009
transmembrane transporter activity 1.07143339827205 bayes_pls_golite062009
substrate-specific transporter activity 1.03753946113449 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.54797726647835 bayes_pls_golite062009
binding 0.509078620937952 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.464663038956639 bayes_pls_golite062009
active transmembrane transporter activity 0.251681382273558 bayes_pls_golite062009
primary active transmembrane transporter activity 0.225448500718996 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.216579620878492 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.177812048124158 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.174283007890308 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.173963339749644 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0401881910649647 bayes_pls_golite062009
pyrophosphatase activity 0.0047964784091391 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle