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Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA. Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA. Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of two substances via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: 4-coumarate-CoA ligase activity
Acc: GO:0016207
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.
Synonyms:
  • 4-coumaryl-CoA synthetase activity
  • p-coumaryl coenzyme A synthetase activity
  • p-hydroxycinnamic acid:CoA ligase activity
  • feruloyl CoA ligase activity
  • sinapoyl coenzyme A synthetase activity
  • feruloyl coenzyme A synthetase activity
  • caffeolyl coenzyme A synthetase activity
  • 4-coumarate:coenzyme A ligase activity
  • 4-coumarate-CoA synthetase activity
  • 4-coumaroyl-CoA synthase activity
  • hydroxycinnamoyl CoA synthetase activity
  • p-coumaroyl CoA ligase activity
  • p-coumaryl-CoA synthetase activity
  • 4-coumarate:CoA ligase (AMP-forming)
  • p-coumaryl-CoA ligase activity
  • 4CL
  • hydroxycinnamate:CoA ligase activity
  • 4-coumarate:CoA ligase activity
  • 4-coumaroyl-CoA synthetase activity
  • p-hydroxycinnamoyl coenzyme A synthetase activity
Proteins in PDR annotated with:
   This term: 26 [Search]
   Term or descendants: 26 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016207 - 4-coumarate-CoA ligase activity (interactive image map)

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