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Protein Overview: gi|23171428, gi|...

General Information:
Name(s) found: gi|24647318 [NCBI NR]
gi|23171428 [NCBI NR]
Description(s) found:
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  • gi|24647318|ref|NP_732097.1| helicase 89B [Drosophila melanogaster] [NCBI NR]
  • gi|23171428|gb|AAF55260.2| helicase 89B [Drosophila melanogaster] [NCBI NR]
  • >CG4261-PA translation from_gene[CG4261 Hel89B FBgn0022787] seq_release:3 mol_weight=213788 cds_boundaries:(3R:11,803,020..11,809,062[+]) aa_length:1929 transcript_info:[CG4261-RA seq_release:3] gene_info:[gene symbol:Hel89B FLAGGED_PROBLEMATIC FBgn002 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VF02) CG4261 protein [DrosMelano7227.FASTAC.txt]
  • CG4261-PA [Drosophila melanogaster]gi|24647318|ref|NP_732097.1| CG4261-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(11803002..11803944,11804009..11806128,11806191..11808232,11808302..11808542,11808604..11809047); ID=FBpp0082668; name=Hel89B-PA; parent=FBgn0022787,FBtr0083214; dbxref=FlyBase:FBpp0082668,FlyBase_Annotation_IDs:CG4261-PA,GB_prote [fly-100309-contam.fasta]
  • CG4261-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Helicase 89B CG4261-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(11803002..11803944,11804009..11806128,11806191..11808232,11808302..11808542,11808604..11809047); ID=FBpp0082668; name=Hel89B-PA; parent=FBgn0022787,FBtr0083214; dbxref=FlyBase:FBpp0082668,FlyBase_Annotation_IDs:CG4261-PA,GB_protein:AAF55260.2,REFSEQ:NP_732097,GB_protein:AAF55260; MD5=0117fa4a82981161a0a96780514ab068; length=1929; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
    • Organism: Drosophila melanogaster
    Length: 1929 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: Toll signaling pathway [IMP]
    innate immune response [IMP]
    antimicrobial humoral response [IMP]
    positive regulation of antibacterial peptide biosynthetic process [IMP]
    Molecular Function: ATP binding [IEA]
    DNA binding [IEA]
    helicase activity [NAS]
    ATP-dependent DNA helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIVFNIPCR LDRLFILLET GSTAATRQAA AKQIGEVQKL YPHELHALLN RLVGYLHSTS  60
   61 WETRIAAAQT VEAILKQVPP WQPEFQVLPK KERCATNTAT AAAAAEEDSC QSSGSNSTTA 120
  121 SERLLSFDEF DLQQILHKGA RLIGSEGNEF DVQEEQPASG GGEEDRSLAS RLSRQRAVLN 180
  181 DKLGLTTAAK LGVNLTDMIT DEDVALNRSG STYNVNAEKL PVEHLLNIKT AANGSGQAPL 240
  241 SCREMNRAKR KARQNTSGCS VTAVTPTCSR RNSNSNHSTG SNHSSNGTTG AAIEEPEKKK 300
  301 LKSTDRQEIF YSLNAAVPDA TGTWVDAVSW PLENFCSRLF IDLFHAKWEV RHGAATALRE 360
  361 LINQHAQGAG KAVLQTREQM DEAHSRWLED AALRLLCVLC LDRFGDFVSD QVVAPVRETC 420
  421 AQVLGTLVKE MEASKVQRIV NILLQLIQHK NEWDVRHGGL LGLKYVFVVR EELLPIYLPQ 480
  481 SISNILIGLL DAVDDVGAVA AATLIPVSSW LPKLLNPAQV SSIVKMLWDL LLDQDELTSA 540
  541 CNSFMGLLAA ILCLPNAARW VEMEPMAILV PRLWPFLSHS TSSVRRSTLK TLMTLTSADR 600
  601 VKSEPKDENQ VKEEADKEEM KLNFGVSDWK WELLQQALRH IYQRILVEPQ ADIQALARQV 660
  661 WSNLIQHADL GALLHAACPF VSSWICLSMQ PPRLAFDAGV LIRAGGDVST PGSTSRKRTP 720
  721 RIGDELGGNI LAQSNASLKL YLGGSEATPL DVRDANFMRA RISSSRALGA LSHYLVQPAP 780
  781 GVVYTPQTES PTDCYTKVLL GHLNAHSAVQ RIVCGLIIAF WALEDEPVRP GPPNLQEKLH 840
  841 QCVSEYVYYD EVAISLTRLL QEAQDFIATL KQNKIPINDF NNAKILTLDQ IEAVATTLSE 900
  901 NLRSYPLKPK VLDMLEERRR SLQASYQQTT SEQSAYHVSA QAALAGAICA LHCLPDKLNP 960
  961 VVKPLMESIK REQCLQLQQL SAEFLVHLMD QVCDRNPSPN SKILNNLCTL LRSDPEFTPK1020
 1021 LVMPLETLKQ TPVSSEVINN CVYYGILTLA LQQTVTTTNT RSGAGGATTP TATTAPRGPG1080
 1081 RPPTGEILSA TNATAHIELK AQQAKEAEAK QCRIQRLGAA CAIEKLCRIF GEQIIEKVAV1140
 1141 FQHLMFGKVE QFVKEAYDWR LGSLLPDLGV CNELVSSMQL IETAAPHLHV ALHPQMFALL1200
 1201 PSLGFIVCHP LKAVRHMAAR CIAVLAEIDA CQTMQFVVHD LLPLLGKIEQ LIERQGAIEA1260
 1261 IERVVSRLQI KVVPYIVLLV VPLLGAMSDP DESVRLLSTH CFANLVQLMP LDGKTEQLKS1320
 1321 DPLQARKTRD REFLDYLFNP KSIPNYKVPV PISVELRCYQ QAGINWLWFL NKYNLHGILC1380
 1381 DDMGLGKTLQ TICILAGDHM HRQTANLANL PSLVICPPTL TGHWVYEVEK FLDQGSVLRP1440
 1441 LHYYGFPVGR EKLRSDIGTK CNLVVASYDT VRKDIDFFSG IHFNYCVLDE GHIIKNGKTK1500
 1501 SSKAIKRLKA NHRLILSGTP IQNNVLELWS LFDFLMPGFL GTEKQFVQRF SRPILSSRDA1560
 1561 KSSAKEQEAG VLAMEALHRQ VLPFLLRRVK EDVLKDLPPK ITQDLLCELS PLQLRLYEDF1620
 1621 SNKHLKDCLD KLGDSSSASM VTENLSAKTH IFQALRYLQN VCNHPKLVLR QSEELTKVTS1680
 1681 QLALSNSSLD DIEHSAKLPA LKQLLLDCGI GVQTESVSQH RALIFCQLKA MLDIVEQDLL1740
 1741 RRHLPSVTYL RLDGSVPASQ RQDIVNNFNS DPSIDVLLLT TMVGGLGLNL TGADTVIFVE1800
 1801 HDWNPMKDLQ AMDRAHRIGQ KKVVNVYRLI TRNSLEEKIM GLQKFKILTA NTVVSAENAS1860
 1861 LQTMGTSQIF DLFNGGKDKG AESGSSAVQG TASGGMSMNT IIENLPELWS EHQYEEEYDL1920
 1921 GNFVQALKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] deduced N/A No confident structure predictions are available.
    2 View Details [115..286] deduced N/A No confident structure predictions are available.
    3 View Details [287..370] deduced N/A No confident structure predictions are available.
    4 View Details [371..1317] FFAS03 2.48 No description for 2ie3A was found.
    5 View Details [1318..1929] PSI-BLAST 97.522879 Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • protein binding
    		•  1.94328873922819 bayes_pls_golite062009
  • binding
    		•  1.62122417417421 bayes_pls_golite062009
  • protein transporter activity
    		•  0.943130585917006 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.675283789558554 bayes_pls_golite062009
  • transporter activity
    		•  0.420208786573211 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.222868189542678 bayes_pls_golite062009
  • catalytic activity
    		•  0.0890324459390017 bayes_pls_golite062009
    5
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  1.69240737024755 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.65296291878002 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.64318297340116 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.64169398852165 bayes_pls_golite062009
  • catalytic activity
    		•  1.37148167194523 bayes_pls_golite062009
  • binding
    		•  1.30574971150356 bayes_pls_golite062009
  • ATPase activity
    		•  1.20060977637766 bayes_pls_golite062009
  • transporter activity
    		•  1.14815595550467 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.08141765801535 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.01232806016411 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.92246823619313 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.89546790004613 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.89065853471483 bayes_pls_golite062009
  • hydrolase activity
    		•  0.875592967682638 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.8668136831732 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.86536264587818 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.86511385357843 bayes_pls_golite062009
  • protein binding
    		•  0.502813311049029 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.495953203188599 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.3056113353665 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.30512981340046 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.30259037403175 bayes_pls_golite062009
  • nucleotide binding
    		•  0.28998663538132 bayes_pls_golite062009
  • DNA binding
    		•  0.128213991729785 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.125640198783258 bayes_pls_golite062009
  • helicase activity
    		•  0.00674361801283974 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.45

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle