Protein Overview: CG5205-PA

General Information:
Name(s) found:	CG5205-PA / FBpp0082601 [FlyBase]
Description(s) found: Found 18 descriptions. SHOW ALL	This gene is referred to in FlyBase by the symbol Dmel\CG5205 (CG5205, FBgn0038344). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11311865..11319033. It has the cytological map location 88F6. Based on sequence similarity, it is predicted to have molecular function</span>: helicase activity; RNA helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	2183 amino acids
Gene Ontology:
Cellular Component:	U5 snRNP [ISS] small nuclear ribonucleoprotein complex [ISS]
Biological Process:	nuclear mRNA splicing, via spliceosome [ISS]
Molecular Function:	nucleic acid binding [IEA] ATP binding [IEA] RNA helicase activity [ISS] ATP-dependent helicase activity [IEA] helicase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWEPPRLSAS LRAKTELEAR SRRLNVLRQA RTTSAASTTT NSQNKEEQTI ARLLAQMPTE  60
   61 KQPAAKVQLQ KLRNLVQECM GYEEQPQVVE HAALFLFWLL LDQRVLLVAT TQRLHGMFGQ 120
  121 TFDRKKTQIH DCVQAIGDLL EDHERSALKR WRQTHHKVPG VGPLWGAHIH VKCTPSEWMD 180
  181 ISLLTDLAPD ALLKNRTVNK FSMKHTTKAA PVASTSSEAA KLSPELQTLL EISAKLDDEH 240
  241 LIIRVGDILG SQRSSEVLQN ELMEILGFDY FELVEKLLME RDKIARQLDQ FATRSRRVME 300
  301 VKQKRMEAAA SGGAAERRPT VASAVVVQSA QEKQLSKMQR REEKKLQRIM RSIKDEEAED 360
  361 DPNCAVAVSV QQLRMQHQRK LLEAAQREPL LLSTKAAKAE YKQSSYNQPI HYPYVFDSQL 420
  421 LAKQHAGFIG GSRITLPDNA QRIDNKQWEE VKIPASEPPP LSVGNKRVQI EELDDVGRLA 480
  481 FANCKELNRI QSVVFPVAYH SNENMLVCAP TGAGKTNVAM LSIVHTIRCH LEQGVINRDE 540
  541 FKIVYIAPMK ALAAEMVDNF SKRLKSLQIA VRELTGDIQL TKAEMAATQI LVTTPEKWDV 600
  601 VTRKGSGDVA LISLVELLII DEVHLLHGER GPVVEALVAR TLRLVESSQS MIRIVGLSAT 660
  661 LPNYIDVAHF LRVNPMKGLF YFDSRFRPVP LDTNFVGIKS VKQLQQIADM DQCCYQKCVE 720
  721 MVQEGHQIMV FVHARNATVR TANVIRELAQ QNNTSALFLP KDSAAHGLAT RSIQRSRNKQ 780
  781 LVELFSCGLA MHHAGMLRAD RQMVEKYFVE GHISVLVCTA TLAWGVNLPA HAVIIRGTDI 840
  841 YDAKHGSFVD LGILDVLQIF GRAGRPQFDK SGVGTIITSY DKLNHYLSLL TNQFPIESNF 900
  901 VNCLADNLNA EIGLGTITNV DEAIEWLSYT YLFVRMRINP HVYGIEYSEL EKDPTLEARR 960
  961 RALIMSAAMS LDKARMMRFN QRTMDMNITD LGRTASYFYI KYDTVETFNE LMKPFMTQAE1020
 1021 ILAMISQAQE FQQLKVRDDE MEELDELKNA YCKIKPYGGS ENVHGKVNIL IQTYLSNGYV1080
 1081 KSFSLSSDMS YITTNIGRIS RALFSIVLRQ NNAVLSGNML QLCKMFERRQ WDFDCHLKQF1140
 1141 PTINAETIDK LERRGLSVYR LRDMEHRELK EWLRSNTYAD LVIRSAHELP LLEVEASLQP1200
 1201 ITRTVLRIKV DIWPSFTWND RVHGKTCQSF WLWIEDPESN YIYHSELFQV TRKLVMSGQS1260
 1261 QQLVMTIPLK EPLPPQYYIR VSSDNWLGST TCIPLSFQHL VLPEHHPPLT ELLPLRPLPV1320
 1321 SCLKNVVYES LYKFTHFNPI QTQIFHCLYH TDNNVLLGAP TGSGKTIVAE IAIFRALNQN1380
 1381 PKCKVVYIAP LKALVKERIA DWEQRFQRSS LGLKVVELTG DVTPDIQAIR ESQLIVTTPE1440
 1441 KWDGISRSWQ TREYVQHVSL IVIDEIHLLG EDRGPVIEVI VSRTNFISSH TGRAIRIVGL1500
 1501 STALANAQDL ANWLGINKMG LYNFKPSVRP VPLQVHINGF PGKHYCPRMA TMNRPTFQAI1560
 1561 RTYSPCEPTI VFVSSRRQTR LTALDLITFV AGESNPKQFL HIPEDEIELI LQNIREQNLK1620
 1621 FCLAFGIGLH HAGLQEQDRK CVEELFLNRK IQILVATATL AWGVNLPAHL VVIKGTEYFD1680
 1681 GKVKKYVDMP ITDVLQMMGR AGRPQFDNEG VAVVLVHDEK KNFYKKFLYD PFPVESSLLG1740
 1741 VLPEHINAEI VAGTVQSKQA ALDYLTWTYF FRRLLRNPSY YQLQDIEPEN VNNFMSNLVE1800
 1801 RVVYELSAAA CLVERDGCLI PTFLGRISSY YYLSYRTMKH FLEDLQPGMN TKKVLLAIAD1860
 1861 SYEFDQLPVR HNEDKHNEEM AEVSRFRPPS SSWDSSYTKT FLLLQAHFAR QSLPNSDYLT1920
 1921 DTKSALDNAT RVMQAMVDYT AERGWLSTTL VVQQLMQSVI QARWFDGSEF LTLPGVNEDN1980
 1981 LDAFLNIPHD DYDYLTLPVL KELCKQEYEV LAKPLRDAFE EHEIEKMYKV IQDLPEIAIQ2040
 2041 IFVEGRHMEN EYAKRPLSLS DDTRGEWMSL HANEDYVLIV NLQRLNVSGQ RRGGGQSYTV2100
 2101 HCPKYPKPKN EAWFLTLGSQ ANDELLAMKR VSIRGQRCTN RISFQATPRL GRLQLTLYLM2160
 2161 SDCLMGFDQQ YDLQFEIIDA KEV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
	4.704140727858	bayes_pls_golite062009
structural constituent of ribosome	3.070470376968	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
RNA binding	2.29590582680214	bayes_pls_golite062009
nucleic acid binding	2.11222585187695	bayes_pls_golite062009
structural molecule activity	2.08211451183607	bayes_pls_golite062009
DNA binding	1.7904783386531	bayes_pls_golite062009
transcription regulator activity	1.68903321260301	bayes_pls_golite062009
RNA helicase activity	1.42791449104435	bayes_pls_golite062009
RNA-dependent ATPase activity	1.39335733374328	bayes_pls_golite062009
ATP-dependent RNA helicase activity	1.36724390116598	bayes_pls_golite062009
snRNA binding	1.20045983086701	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
mRNA binding	0.76699944561918	bayes_pls_golite062009
helicase activity	0.6191010101321	bayes_pls_golite062009
transcription factor activity	0.603758349693077	bayes_pls_golite062009
purine nucleotide binding	0.569910969126728	bayes_pls_golite062009
purine ribonucleotide binding	0.568840867400671	bayes_pls_golite062009
ribonucleotide binding	0.568779924702229	bayes_pls_golite062009
nucleotide binding	0.564275755355315	bayes_pls_golite062009
purine NTP-dependent helicase activity	0.29664013896754	bayes_pls_golite062009
ATP-dependent helicase activity	0.29664013896754	bayes_pls_golite062009
translation regulator activity	0.29096092258568	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.274994961137851	bayes_pls_golite062009
ATP binding	0.1860481660648	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009
adenyl ribonucleotide binding	0.152859582615242	bayes_pls_golite062009
adenyl nucleotide binding	0.138615225841109	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.0530667986761242	bayes_pls_golite062009
pyrophosphatase activity	0.0482442222493492	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.028470639373934	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0265151533232588	bayes_pls_golite062009

No functions predicted.

Term	Confidence	Notes
structural molecule activity	2.80935217964088	bayes_pls_golite062009
binding	2.65544526722793	bayes_pls_golite062009
protein binding	1.50286160643298	bayes_pls_golite062009
ligand-gated ion channel activity	0.423207248971435	bayes_pls_golite062009
ligand-gated channel activity	0.423207248971435	bayes_pls_golite062009
cytoskeletal protein binding	0.42238661903557	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..100]	deduced	N/A	No confident structure predictions are available.
2	View Details	[101..218]	MSA	1.139989	View MSA. No confident structure predictions are available.
3	View Details	[219..412]	deduced	N/A	No confident structure predictions are available.
4	View Details	[413..481]	PSI-BLAST	71.30103	No description for 2j0qA was found.
5	View Details	[482..725]	PSI-BLAST	6.522879	No description for 2v8oA was found.
6	View Details	[726..1887]	PSI-BLAST	47.69897	Crystal structure of Escherichia coli transcription-repair coupling factor
7	View Details	[1888..2017]	PSI-BLAST	84.0	No description for 2p6rA was found.
8	View Details	[2018..2183]	PSI-BLAST	79.69897	No description for 2q0zX was found.

Protein Overview: CG5205-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: