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Protein Overview: stck-PB

General Information:
Name(s) found: stck-PB / FBpp0081335 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene steamer duck is referred to in FlyBase by the symbol Dmel\stck (CG7954, FBgn0020249). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4182689..4185745. It has the cytological map location 84F15. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: dorsal closure; apposition of dorsal and ventral imaginal disc-derived wing surfaces; embryonic pattern specification; negative regulation of JNK cascade; head involution. 14 alleles are reported. The phenotypes of these alleles are annotated with: larva; embryonic somatic muscle; embryonic/larval somatic muscle. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 345 amino acids

    Gene Ontology:
    Cellular Component: cell leading edge [IDA]
    Biological Process: dorsal closure [IMP]
    embryonic pattern specification [IMP]
    head involution [IMP]
    apposition of dorsal and ventral imaginal disc-derived wing surfaces [IMP]
    negative regulation of JNK cascade [IGI]
    Molecular Function: zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPVQVQAAN MSLGAMHCTR CADGFEPTEK IVNSNGELWH TQCFVCAQCF RPFQDGIFYE  60
   61 FEGRKYCERD FHVLFAPCCN KCGEFVIGRV IKAMSASWHP QCFRCQLCAK ELADCGFIKN 120
  121 QNRALCHECN AKVKAEITGR YVCQKCHGLI DEEPLRFRGE VYHGYHFSCT ACGTELDSTA 180
  181 REVKSRPGLA ANDMNELYCL RCHDKMGIPI CGACRRPIEE RVVTALGKHW HVEHFVCAKC 240
  241 EKPFLGHRHY EKRGLAYCET HYHQLFGNLC FVCNQVIGGD VFTALNKAWC VHHFACSVCD 300
  301 TKMTQKSKFY EYDEKPVCKK CYDRFPNELR RRLRTAHEMT MKKNT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] PSI-BLAST 48.69897 No description for 2i13A was found.
    2 View Details [196..345] PSI-BLAST 13.30103 Five-finger GLI1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription activator activity
    		•  3.52873291636993 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.53101891154822 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.22104591928521 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • protein binding
    		•  2.05530362750351 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.64349785387632 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.12277938241964 bayes_pls_golite062009
  • signal transducer activity
    		•  1.12277938241964 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.93314267845352 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • tubulin binding
    		•  0.744315484113484 bayes_pls_golite062009
  • microtubule binding
    		•  0.576452165256057 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.53991278722671 bayes_pls_golite062009
  • receptor activity
    		•  0.36635758793995 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.10558148421807 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle