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Protein Overview: enok-PA, FBpp0309997

General Information:
Name(s) found: FBpp0309997 [FlyBase]
enok-PA / FBpp0072159 [FlyBase]
Description(s) found:
Found 25 descriptions.
SHOW ALL
  • type=protein; loc=2R:join(19987404..19988266,19988326..19988409,19988470..19993213,19993278..19994462); ID=FBpp0309997; name=enok-PB; parent=FBgn0034975,FBtr0343339; dbxref=FlyBase:FBpp0309997,FlyBase_Annotation_IDs:CG11290-PB; MD5=2f658ca3a4f3bd1ad11af9842b4caf7a; length=2291; release=r5.56; species=Dmel; [FlyBase]
  • The gene enoki mushroom is referred to in FlyBase by the symbol Dmel\enok (CG11290, FBgn0034975). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19987404..19994557. It has the cytological map location 60B10. Based on sequence similarity, it is predicted to have molecular function</span>: histone acetyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: neuroblast proliferation; mushroom body development. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2291 amino acids

    Gene Ontology:
    Cellular Component: nucleosome [IEA]
    histone acetyltransferase complex [ISS]
    Biological Process: neuroblast proliferation [IMP]
    mushroom body development [IMP]
    regulation of transcription [IEA]
    nucleosome assembly [IEA]
    Molecular Function: histone acetyltransferase activity [ISS]
    DNA binding [IEA]
    zinc ion binding [IEA]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRESAHDIN MDTWNQWILE AISKIRSQKQ RPSVQRICQA IGTHHKFHED IVAEKLEKAV  60
   61 ESGAVIKVYN KGLHSYKAPM AKRRVKVDKN TNLYKLVAKA VHDLGECEGS TIKSIENYIQ 120
  121 KFNCIDLSPN VDFKAVIKAS IKKAVDAGFL IQEGKLYKKG KSLTTPRKCA PVSEVVIKGE 180
  181 ESCTHCSGNS QKNLNGIPEP LSSCKQCGIS LHTTCANIAG RCKSQSYVLL YMLVTKGTIW 240
  241 DCQNCADCAV CKMRNRGPCL LQCFVCKDHF HLTCLDTIPD KKPKHPYRCK TCSKQGFDTP 300
  301 KLVKKDNSRI KMEAERMTPS YKYASNKRQS IKKDGNIESP STSKLCVYND GNGQRRKVPA 360
  361 SLSSRKMNHS EDQFEFPSKQ KRSQILQGGY LASQETRKRT FSDLSSTSSS SESEDEDDED 420
  421 DDRNRNGDDN DQDESTSSDS CTSSSSDSDS SESSSDTSEW DDEYDEEEDY DTDRSTIREK 480
  481 NVFESGKQSC AKLSTGDGLG SPQNNELGSE NWGFAAVAKN PIDIFVKSKH NSNVKGIGYS 540
  541 KPAASTFATS PAANRVQKST PVASSTPEKN SAPIGGMTIK RQTANGQKKK IVPLKSMPLE 600
  601 AGKSYEKCED DIPYLTEETV MKVQLLEEIE RSRETHSQAD GKREMNNDED APGESTKRAN 660
  661 PFENQPLPPG VTATDVELYQ EVLHKAVVQM SNNHIEKVND VSLKSGQNTQ SPKSIQIGKW 720
  721 DIETWYSSPF PQEYARLLKL FLCEFCLKYT KSRSVLDRHQ NKCIWKQPPG TEIFRQGNIS 780
  781 VFEVDGNVNK IYCQNLCLLA KFFLDHKTLY YDVEPFLFYI LTKNDQSGCH LVGYFSKEKH 840
  841 CTQKYNVSCI LTMPQYQRQG YGRFLIDFSY LLSREEGQLG TPEKPLSDLG RLSYFSYWKS 900
  901 VVLEYLYKHR NYTKITFKDI AIKTGLAISD IALAFELLNF IKLRKNDGDI RYQINVKIEW 960
  961 KKVLAHHNKM ANSKTRIIIE PDCLRWSPLL SVSKLPNIIK PISNREYLSN QMETNSSFKE1020
 1021 INEDKISVKQ GVSTSSKVNQ ESSELSTKNR GPSSEKLIDE RENQRKRAYP EEFLKSASNE1080
 1081 AKKPKLTAPQ PNLEDQSFGE LSDSSDCKSS KDLSEQLTKR AQRLAKRNDL IPHTNKRKHF1140
 1141 DRPLENNTTS TDHNPPAQSQ ADTAGTENGH KSEETAAKEN CKNVVEKEHV DKPVNIMPKL1200
 1201 RGKQSNGKRS EEPQFNENPT SDPVAVASLS PAKEITREPV KVAKTESPGK NQESAKHDAE1260
 1261 PNSVSDQVLD AVAKKTKKTL FSDVASYNTE DVKYNSEEKP MAIAQEPKES PTEAGIKETK1320
 1321 PLEVPEQKAK AKSPEKPATV AETVLQHVHA PVNTEKISTE ESKLELDVHY LKLSPDSALN1380
 1381 PPVASVQKPV PEPPAPKEKA KDLQAAQPSE ALQKQPEIEM VKKTETKTET PVSNPPSNRT1440
 1441 DVSSLVEQPV KAAPEKVEQP MVKEAVDIKD KALKKPVPDV PVVKPEATSC EKKIDHSKTK1500
 1501 VFHEKEAIKT DQQLVQVKEE EKSNARAPSA PIPIRDKIQL KGNEHAQLQN SIPSQFPLNQ1560
 1561 MPNYHTSQYW QWEYYGYNLS HLDASQKGQK QFHKDLATTM AYTHNFTQNL YQSANLAMQH1620
 1621 AHHQMHQTKE KHKVERKNSG KKEEQNKVVS SVNVVSTARE DAHVQHCNEY AANNQAALYN1680
 1681 QKCASQQKQA QQMKSLANVQ NPVPRQSNSN APESTVLMPN PVISQAGSVP AKQKVEHGVN1740
 1741 STSVISREGK LNKIGHSNIH ATAQHANLQV GGGQSDVNPN MVYNTESSAN SAMQHYDCGI1800
 1801 SAQINMDSPA NIGSAIAHGP QEISATSNVH MHQPHRQFSD CSMQNQPVTT PMHMSIQNSH1860
 1861 MQQQNNLNLN LAPEGSSNIN LLSNPQHQHQ SRKLNAQADI AVSSPTPSHR ATTPKQIRSG1920
 1921 NTQQRDAKNA APPTTTTNTH HQIPQGGAAA NISKSHHDSL HNLQFSQHGH QQNMQPIDYV1980
 1981 PIPQISQNFS ANPSNYDIVG MPAVIQQRMS LNGSVHSLAN SHQRIEQPSS ACAVNNFYLQ2040
 2041 NNMPAAENAP RVPVSSSLGG PPTAGNNDQR QAGQDSITTA NSSGATASLA GNLCSLSKLQ2100
 2101 QLTNCLESQP CNTSPGAQVN LAPSPHHPIP PNSTPPPHLL MQNRNISTPP NMLQTQVTPL2160
 2161 QYKYYPGNMN IPPITSAQNT SRNTRNTPSA PVQHTSTPMG SGNNRTANVH ISPNLMAPYG2220
 2221 AINSYRMSPQ QSPPTGSYSS GGDYPNSQIP MQMMNMQSQY QDACVLQRGT PSNPMYPTYS2280
 2281 PYLPLNGSIR R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] deduced N/A No confident structure predictions are available.
    2 View Details [83..179] FFAS03 3.78 YEAST HISTONE H1 GLOBULAR DOMAIN II, HHO1P GII, SOLUTION NMR STRUCTURES
    3 View Details [180..295] PSI-BLAST 25.39794 No description for 2ysmA was found.
    4 View Details [296..376] PSI-BLAST 7.30103 No description for 2f6jA was found.
    5 View Details [377..491] deduced N/A No confident structure predictions are available.
    6 View Details [492..577] deduced N/A No confident structure predictions are available.
    7 View Details [578..700] deduced N/A No confident structure predictions are available.
    8 View Details [701..992] PSI-BLAST 134.0 No description for 2ozuA was found.
    9 View Details [993..1067] deduced N/A No confident structure predictions are available.
    10 View Details [1068..1151] deduced N/A No confident structure predictions are available.
    11 View Details [1152..1258] deduced N/A No confident structure predictions are available.
    12 View Details [1259..1505] deduced N/A No confident structure predictions are available.
    13 View Details [1506..1579] deduced N/A No confident structure predictions are available.
    14 View Details [1580..1647] deduced N/A No confident structure predictions are available.
    15 View Details [1648..1731] deduced N/A No confident structure predictions are available.
    16 View Details [1732..1975] deduced N/A No confident structure predictions are available.
    17 View Details [1976..2186] deduced N/A No confident structure predictions are available.
    18 View Details [2187..2291] MSA 2.347987 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.23858959608048 bayes_pls_golite062009
  • DNA binding
    		•  4.78517210147551 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.72059012764202 bayes_pls_golite062009
  • transcription factor activity
    		•  4.02736190679869 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.60278632732466 bayes_pls_golite062009
  • transcription activator activity
    		•  3.46623224639317 bayes_pls_golite062009
  • binding
    		•  3.37660003833383 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.31558616762587 bayes_pls_golite062009
  • protein binding
    		•  1.77689943618029 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.50332889556988 bayes_pls_golite062009
  • transcription factor binding
    		•  0.752335897765285 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.710995647413393 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.451714629708561 bayes_pls_golite062009
  • structural molecule activity
    		•  0.288722664470538 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.281229260644949 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.252392400929265 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.206400521000307 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.112565538295256 bayes_pls_golite062009
  • transferase activity
    		•  0.10058871838551 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.
    11 No functions predicted.
    12 No functions predicted.
    13 No functions predicted.
    14 No functions predicted.
    15 No functions predicted.
    16 No functions predicted.
    17 No functions predicted.
    18 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle