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View Structure Prediction Details

Protein: enok-PA, FBpp0309997
Organism: Drosophila melanogaster
Length: 2291 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for enok-PA, FBpp0309997.

Description E-value Query
Range		 Subject
Range
gi|73953062 - gi|73953062|ref|XP_536397.2| PREDICTED: similar to Histone acetyltransferase MYST4 (MYST protein 4) ...
 1106.0 [0..9] [2093..4]

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Predicted Domain #1
Region A:
Residues: [1-82] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRESAHDIN MDTWNQWILE AISKIRSQKQ RPSVQRICQA IGTHHKFHED IVAEKLEKAV  60
   61 ESGAVIKVYN KGLHSYKAPM AK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [83-179] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRVKVDKNTN LYKLVAKAVH DLGECEGSTI KSIENYIQKF NCIDLSPNVD FKAVIKASIK  60
   61 KAVDAGFLIQ EGKLYKKGKS LTTPRKCAPV SEVVIKG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.78
Match: 1ussA
Description: YEAST HISTONE H1 GLOBULAR DOMAIN II, HHO1P GII, SOLUTION NMR STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.23858959608048 bayes_pls_golite062009
DNA binding 4.78517210147551 bayes_pls_golite062009
nucleic acid binding 4.72059012764202 bayes_pls_golite062009
transcription factor activity 4.02736190679869 bayes_pls_golite062009
transcription repressor activity 3.60278632732466 bayes_pls_golite062009
transcription activator activity 3.46623224639317 bayes_pls_golite062009
binding 3.37660003833383 bayes_pls_golite062009
sequence-specific DNA binding 3.31558616762587 bayes_pls_golite062009
protein binding 1.77689943618029 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.50332889556988 bayes_pls_golite062009
transcription factor binding 0.752335897765285 bayes_pls_golite062009
specific transcriptional repressor activity 0.710995647413393 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.451714629708561 bayes_pls_golite062009
structural molecule activity 0.288722664470538 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.281229260644949 bayes_pls_golite062009
transcription corepressor activity 0.252392400929265 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.206400521000307 bayes_pls_golite062009
structural constituent of ribosome 0.112565538295256 bayes_pls_golite062009
transferase activity 0.10058871838551 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [180-295] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EESCTHCSGN SQKNLNGIPE PLSSCKQCGI SLHTTCANIA GRCKSQSYVL LYMLVTKGTI  60
   61 WDCQNCADCA VCKMRNRGPC LLQCFVCKDH FHLTCLDTIP DKKPKHPYRC KTCSKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.39794
Match: 2ysmA
Description: No description for 2ysmA was found.

Predicted Domain #4
Region A:
Residues: [296-376] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFDTPKLVKK DNSRIKMEAE RMTPSYKYAS NKRQSIKKDG NIESPSTSKL CVYNDGNGQR  60
   61 RKVPASLSSR KMNHSEDQFE F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 2f6jA
Description: No description for 2f6jA was found.

Predicted Domain #5
Region A:
Residues: [377-491] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSKQKRSQIL QGGYLASQET RKRTFSDLSS TSSSSESEDE DDEDDDRNRN GDDNDQDEST  60
   61 SSDSCTSSSS DSDSSESSSD TSEWDDEYDE EEDYDTDRST IREKNVFESG KQSCA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [492-577] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLSTGDGLGS PQNNELGSEN WGFAAVAKNP IDIFVKSKHN SNVKGIGYSK PAASTFATSP  60
   61 AANRVQKSTP VASSTPEKNS APIGGM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [578-700] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIKRQTANGQ KKKIVPLKSM PLEAGKSYEK CEDDIPYLTE ETVMKVQLLE EIERSRETHS  60
   61 QADGKREMNN DEDAPGESTK RANPFENQPL PPGVTATDVE LYQEVLHKAV VQMSNNHIEK 120
  121 VND

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [701-992] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSLKSGQNTQ SPKSIQIGKW DIETWYSSPF PQEYARLLKL FLCEFCLKYT KSRSVLDRHQ  60
   61 NKCIWKQPPG TEIFRQGNIS VFEVDGNVNK IYCQNLCLLA KFFLDHKTLY YDVEPFLFYI 120
  121 LTKNDQSGCH LVGYFSKEKH CTQKYNVSCI LTMPQYQRQG YGRFLIDFSY LLSREEGQLG 180
  181 TPEKPLSDLG RLSYFSYWKS VVLEYLYKHR NYTKITFKDI AIKTGLAISD IALAFELLNF 240
  241 IKLRKNDGDI RYQINVKIEW KKVLAHHNKM ANSKTRIIIE PDCLRWSPLL SV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 134.0
Match: 2ozuA
Description: No description for 2ozuA was found.

Predicted Domain #9
Region A:
Residues: [993-1067] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKLPNIIKPI SNREYLSNQM ETNSSFKEIN EDKISVKQGV STSSKVNQES SELSTKNRGP  60
   61 SSEKLIDERE NQRKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1068-1151] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYPEEFLKSA SNEAKKPKLT APQPNLEDQS FGELSDSSDC KSSKDLSEQL TKRAQRLAKR  60
   61 NDLIPHTNKR KHFDRPLENN TTST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1152-1258] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHNPPAQSQA DTAGTENGHK SEETAAKENC KNVVEKEHVD KPVNIMPKLR GKQSNGKRSE  60
   61 EPQFNENPTS DPVAVASLSP AKEITREPVK VAKTESPGKN QESAKHD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1259-1505] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEPNSVSDQV LDAVAKKTKK TLFSDVASYN TEDVKYNSEE KPMAIAQEPK ESPTEAGIKE  60
   61 TKPLEVPEQK AKAKSPEKPA TVAETVLQHV HAPVNTEKIS TEESKLELDV HYLKLSPDSA 120
  121 LNPPVASVQK PVPEPPAPKE KAKDLQAAQP SEALQKQPEI EMVKKTETKT ETPVSNPPSN 180
  181 RTDVSSLVEQ PVKAAPEKVE QPMVKEAVDI KDKALKKPVP DVPVVKPEAT SCEKKIDHSK 240
  241 TKVFHEK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #13
Region A:
Residues: [1506-1579] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAIKTDQQLV QVKEEEKSNA RAPSAPIPIR DKIQLKGNEH AQLQNSIPSQ FPLNQMPNYH  60
   61 TSQYWQWEYY GYNL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #14
Region A:
Residues: [1580-1647] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHLDASQKGQ KQFHKDLATT MAYTHNFTQN LYQSANLAMQ HAHHQMHQTK EKHKVERKNS  60
   61 GKKEEQNK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #15
Region A:
Residues: [1648-1731] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVSSVNVVST AREDAHVQHC NEYAANNQAA LYNQKCASQQ KQAQQMKSLA NVQNPVPRQS  60
   61 NSNAPESTVL MPNPVISQAG SVPA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #16
Region A:
Residues: [1732-1975] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQKVEHGVNS TSVISREGKL NKIGHSNIHA TAQHANLQVG GGQSDVNPNM VYNTESSANS  60
   61 AMQHYDCGIS AQINMDSPAN IGSAIAHGPQ EISATSNVHM HQPHRQFSDC SMQNQPVTTP 120
  121 MHMSIQNSHM QQQNNLNLNL APEGSSNINL LSNPQHQHQS RKLNAQADIA VSSPTPSHRA 180
  181 TTPKQIRSGN TQQRDAKNAA PPTTTTNTHH QIPQGGAAAN ISKSHHDSLH NLQFSQHGHQ 240
  241 QNMQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #17
Region A:
Residues: [1976-2186] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIDYVPIPQI SQNFSANPSN YDIVGMPAVI QQRMSLNGSV HSLANSHQRI EQPSSACAVN  60
   61 NFYLQNNMPA AENAPRVPVS SSLGGPPTAG NNDQRQAGQD SITTANSSGA TASLAGNLCS 120
  121 LSKLQQLTNC LESQPCNTSP GAQVNLAPSP HHPIPPNSTP PPHLLMQNRN ISTPPNMLQT 180
  181 QVTPLQYKYY PGNMNIPPIT SAQNTSRNTR N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #18
Region A:
Residues: [2187-2291] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPSAPVQHTS TPMGSGNNRT ANVHISPNLM APYGAINSYR MSPQQSPPTG SYSSGGDYPN  60
   61 SQIPMQMMNM QSQYQDACVL QRGTPSNPMY PTYSPYLPLN GSIRR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle