YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: fd59A-PA

General Information:
Name(s) found: fd59A-PA / FBpp0071809 [FlyBase]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • The gene forkhead domain 59A is referred to in FlyBase by the symbol Dmel\fd59A (CG3668, FBgn0004896). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18754044..18758229. It has the cytological map location 59B4. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 456 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS][NAS]
    Biological Process: embryonic development [NAS]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription from RNA polymerase II promoter [ISS]
    Molecular Function: transcription factor activity [ISS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTSTDPMHT LHDSVSLSPP LIKSSRGGSS IGNGIGCSAS SRTAAADAMS MGCDDSDIEP  60
   61 SSMGGSGAAG GNGDGSGSSG GPLVKPPYSY IALITMAILQ SPHKKLTLSG ICDFIMSRFP 120
  121 YYKDKFPAWQ NSIRHNLSLN DCFIKVPREP GNPGKGNFWT LDPLAEDMFD NGSFLRRRKR 180
  181 YKRAPTMQRF SFPAVFGTLS PFWIRKPVPL VPVHFNVPNF NGSREFDVVH NPADVFDSAL 240
  241 RADKKFNFFA NAEASFYQGS QSGDKFDRLP FMNRGRGADV LDALPHSSGS GGGVGGGSES 300
  301 SRGSKYKSPY AFDVATVASA AGIPGHRDYA ERLSAGGGYM DLNVYNDDAD TEADAEAEGD 360
  361 DDSCEDKIDV ESGNEQEDSH ISDSVDSACT NRLDAPPEAL IFEASAEASD SSPRRRFDSE 420
  421 PLVLRTSKQS SAKDFRIETL IGHHLHRGGS QEETSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] deduced N/A No confident structure predictions are available.
    2 View Details [74..182] PSI-BLAST 35.39794 Genesis
    3 View Details [183..351] MSA 4.455996 View MSA. No confident structure predictions are available.
    4 View Details [352..456] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.99681957904233 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.85678231380989 bayes_pls_golite062009
  • transcription activator activity
    		•  3.70589483230587 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.58179858678904 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.60738445921725 bayes_pls_golite062009
  • protein binding
    		•  1.80415286835431 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.2723726467408 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.96257232341735 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.66743181561551 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.322180400748724 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.23177057841536 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.59

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle