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Protein Overview: CG11208-PA

General Information:
Name(s) found: CG11208-PA / FBpp0085630 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG11208 (CG11208, FBgn0034488). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16130256..16132904. It has the cytological map location 56F11. Based on sequence similarity, it is predicted to have molecular function</span>: oxalyl-CoA decarboxylase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 568 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: magnesium ion binding [IEA]
    thiamin pyrophosphate binding [IEA]
    oxalyl-CoA decarboxylase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEVEAVQII AESLKQQGVE YVFGIIGIPV IELSMAFQAA GLKYIGMRNE QAACYAAQAI  60
   61 GYLTGKPGVC LVVSGPGLLH VTGGMANAQV NCWPLIVIGG ATNQDHEGIG GFQECPQVEL 120
  121 SRPYCKYAAR PATAALIPLH VEKAVRYATY GRPGVAYLDF PGNILQSKAQ EASIYKALAH 180
  181 PAPPLAYPPH DDVIRAAKLL RQAKRPLVIV GKGSAYAHAE NTLRHFIENT NLPFLPTPMG 240
  241 KGVVSDTAPQ CVSSARTLAL QKADVVLLLG ARLNWILHFG KAPRYDKDVK FIQVDINPEE 300
  301 LHNSVVASVA IQADIRPFAE QLFEQMNAVN FRFGYEQDWW KQLAVKCKQN RDTVQKMSLN 360
  361 TETPLNYYAV FHHLRELLPK DTIIVSEGAN TMDIGRSMLL NEQPRHRLDA GTFGTMGVGP 420
  421 GFAVAAALFC RDFAPGKRVL CVEGDSAFGF SGMEIETMVR YKLPVTIVIV NNNGIYGGFD 480
  481 KDTFEAIRSE GDLTQITPPS ALGVQVRYEE MMKMFGMKGY FCTEIEQLQA AVKAANQLTD 540
  541 RPTIINVAIS PSSDRKPQSF NWLTESKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..568] PSI-BLAST 94.522879 CRYSTAL STRUCTURE OF OXALYL-COA DECARBOXYLASE IN COMPLEX WITH THE COFACTOR DERIVATIVE THIAMIN-2-THIAZOLONE DIPHOSPHATE AND ADENOSINE DIPHOSPHATE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetolactate synthase activity
    		•  12.903449876837 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  12.3239025230705 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  5.28857071459273 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  5.21233670052586 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  5.08663245333808 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.51117258094456 bayes_pls_golite062009
  • catalytic activity
    		•  2.25537597692103 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  2.15444163802756 bayes_pls_golite062009
  • DNA binding
    		•  2.09930834951157 bayes_pls_golite062009
  • deoxyhypusine synthase activity
    		•  2.04735838056767 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.00972611627502 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  1.98546381612935 bayes_pls_golite062009
  • NAD-dependent histone deacetylase activity
    		•  1.93141177609772 bayes_pls_golite062009
  • NAD-dependent protein deacetylase activity
    		•  1.93141177609772 bayes_pls_golite062009
  • histone deacetylase activity
    		•  1.91254869751164 bayes_pls_golite062009
  • protein deacetylase activity
    		•  1.90521776801103 bayes_pls_golite062009
  • thiamin pyrophosphate binding
    		•  1.87247313698582 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.82969293063325 bayes_pls_golite062009
  • transketolase activity
    		•  1.70348931648612 bayes_pls_golite062009
  • binding
    		•  1.17940168894417 bayes_pls_golite062009
  • transcription factor binding
    		•  1.07103864164531 bayes_pls_golite062009
  • 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
    		•  1.07090849835369 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.0611726850452 bayes_pls_golite062009
  • transcription factor activity
    		•  1.0180828203704 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.98460927780383 bayes_pls_golite062009
  • deacetylase activity
    		•  0.977680867213479 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.78591260444574 bayes_pls_golite062009
  • alpha-ketoacid dehydrogenase activity
    		•  0.750929351082237 bayes_pls_golite062009
  • hydrolase activity
    		•  0.536729211484905 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.516307124442946 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.51426028502998 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.492590326775569 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.42635585193838 bayes_pls_golite062009
  • transferase activity
    		•  0.413024577830522 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.23414654967509 bayes_pls_golite062009
  • pyruvate decarboxylase activity
    		•  0.198062360371269 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.114062221123972 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.41

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle