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Protein Overview: CG4439-PA

General Information:
Name(s) found: CG4439-PA / FBpp0086235 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4439 (CG4439, FBgn0034132). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12378605..12380738. It has the cytological map location 53C6. Based on sequence similarity, it is predicted to have molecular function</span>: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 534 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: proteolysis [IEA]
    Molecular Function: metalloexopeptidase activity [IEA]
    aminopeptidase activity [ISS]
    manganese ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRSQMISSL RRSTLGLFRC HKALIFARIP AFQQVRCKSE DGSCNTCNLQ GVVVGLYAKD  60
   61 GDKGLKLSPG GEKFDDRVGG KITELIKESG LNGELGVGRL YQNIDKEYWA VAVVGLGKEG 120
  121 AGFNAEEVID EGMENVRVCA AVGARALQLQ GCTTCHVDGM EYPEQAAEGA AMAVWRYNVN 180
  181 KRKKNRIAIP KLELYGSTDQ DAWTRGLFKA ESQNLARRLS DTPANQMTPS IFAQATVDAL 240
  241 CPCGVSVEVR SMDWIETQNL NSFLMVAKGS CEPPIILEVS YCGTSPEERP ILMLGKGLTF 300
  301 NSGGLCLHPK RGMDEYRGAV SGAAVCVAAI RAAAALSLPI NVSAVLPLCE NMPSGMATKP 360
  361 GDVVTLLNGK TMRIKDISLA GTVLLADPLL YAQSTFKPKL VVEVGSMASG IRKGLGASAT 420
  421 GLWTNNSFLW KNFQKAGALT GDRLWRMPLW RYFRKLVAPR ASYDICSTGE GHASSCLAAA 480
  481 ILYELVPCSD WVHLDTHGTG MLAKHGVPPY LLKDCMTGRP TRSIIQFLYQ MACK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..534] PSI-BLAST 154.0 No description for 2ewbA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  3.26568153906254 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.98334117181651 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.06343447704714 bayes_pls_golite062009
  • binding
    		•  1.93664040569212 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.62070628167746 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.5759162922092 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.19646763645944 bayes_pls_golite062009
  • DNA binding
    		•  1.19591446544558 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.891655769761122 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  0.472688733072762 bayes_pls_golite062009
  • protein binding
    		•  0.4345997482448 bayes_pls_golite062009
  • hydrolase activity
    		•  0.367195794753195 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  0.180859448845431 bayes_pls_golite062009
  • catalytic activity
    		•  0.168716604730246 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.0966237570696103 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle