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Protein Overview: CG18369-PA

General Information:
Name(s) found: CG18369-PA / FBpp0086750 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG18369 (CG18369, FBgn0033860). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9484182..9486255. It has the cytological map location 50B4-50B5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. There is experimental evidence that it is involved in the biological process</span>: mesoderm development. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 549 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: proteolysis [IEA]
    mesoderm development [IEP]
    Molecular Function: metalloexopeptidase activity [IEA]
    manganese ion binding [IEA]
    aminopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTRMISAF TRNPRLYQQV TAPWKSYNLF GTPLFNHRLQ PADSQIWRGL ADKCDNKTVI  60
   61 KGVVVGVYSK EGDGKEVKMT SSGEKFDDRT QGKVSELLRE TGIKGELGKG KVFMNVDAEF 120
  121 RAVAVVGLGQ EGAGFNDLEN IDEGMENARV AAGVGARALQ LQGCTEVFVD SMEYPEQAAE 180
  181 GSALAIWRYN SNKRKQDRTQ VPKLDLYDSP DVDAWTRGLF KAESQNLARR LSDSPANQMT 240
  241 PTIFAQSAVD ALCPCGVSVE VRSMDWIEMN HLNSFLMIAK GSCEPPVVLE VSYCGTAPED 300
  301 RPILLLGKGL TYNSGGLCLR PKDCLHMYRG CMAGAAVCVA AVRAAAALSL PVNITAVLPL 360
  361 CENMPSGMAV KPGDVVTLLN GKTMGIVDVS KAGTVVLADP LLFAQTTYKP RLVVDLATVG 420
  421 YGVCAGLGES AAGLFTNSNF IAKQFEKAGG LTGDRLWRLP LWRYFKQLVT PNLTFDISNR 480
  481 GIGPASSCIA AAVLHELVPC ADWAHIDIRN VGMLTRHNPL PYLLKDRMTG RPTRTIVQFL 540
  541 YQMACPESK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..549] PSI-BLAST 155.0 No description for 2ewbA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  3.26568153906254 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.98334117181651 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.06343447704714 bayes_pls_golite062009
  • binding
    		•  1.93664040569212 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.62070628167746 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.5759162922092 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.19646763645944 bayes_pls_golite062009
  • DNA binding
    		•  1.19591446544558 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.891655769761122 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  0.472688733072762 bayes_pls_golite062009
  • protein binding
    		•  0.4345997482448 bayes_pls_golite062009
  • hydrolase activity
    		•  0.367195794753195 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  0.180859448845431 bayes_pls_golite062009
  • catalytic activity
    		•  0.168716604730246 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.0966237570696103 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle