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Protein Overview: Mat1-PA

General Information:
Name(s) found: Mat1-PA / FBpp0087350 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Mat1 is referred to in FlyBase by the symbol Dmel\Mat1 (CG7614, FBgn0024956). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6626122..6627339. It has the cytological map location 47B9. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription initiation from RNA polymerase II promoter. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 320 amino acids

    Gene Ontology:
    Cellular Component: holo TFIIH complex [ISS]
    Biological Process: transcription initiation from RNA polymerase II promoter [ISS]
    cell cycle [IEA]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IEA]
    general RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDQACPRCK TTKYRNPSLK LMVNVCGHTL CESCVDLLFL KGSGACPECM VPLRRNNFRV  60
   61 QLFEDPMVEK EVDIRRRILR DYNKREEDFA SLAEYNDYLE EIEDIVYNLC NNIDIIETNK 120
  121 RIEAYKRDNR EVIQRNKTRV GRDEYALEEM LELEKVQEEA RRKELEELEN EHKKKKARDK 180
  181 QALIEELMYS GKDAAQIVTE FAEKAEKQRE EEKQLPPPKP ANEFSTGIKF GQTADPSLLP 240
  241 VPKSEEGPLF VYEPLVPFSE GPAMPPTNEI VSRGYIAHIR AETPQENAGG FTSALACERA 300
  301 LQEALQGLYY TATTGVVSGT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..63] PSI-BLAST 12.69897 TFIIH Mat1 subunit
    2 View Details [64..320] PSI-BLAST 4.154902 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  6.51043144330453 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  3.14238164427954 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  3.12673603940339 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.72498741013971 bayes_pls_golite062009
  • protein binding
    		•  2.64803540957326 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.32387297115017 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.10988747259202 bayes_pls_golite062009
  • DNA binding
    		•  2.00904221080834 bayes_pls_golite062009
  • transcription activator activity
    		•  1.45530270292081 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22579085356684 bayes_pls_golite062009
  • transcription factor binding
    		•  1.11842175076436 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.926364718530146 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.90321253993065 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.350170315296021 bayes_pls_golite062009
  • ligase activity
    		•  0.34187399168736 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.255669498391574 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.233838999434784 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • enzyme binding
    		•  0.104373352314595 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.024993043379745 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle