Protein Overview: lok-PA

General Information:
Name(s) found:	lok-PA / FBpp0080860 [FlyBase]
Description(s) found: Found 22 descriptions. SHOW ALL	The gene loki is referred to in FlyBase by the symbol Dmel\lok (CG10895, FBgn0019686). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:20061477..20064381. It has the cytological map location 38B2. Based on sequence similarity, it is predicted to have molecular function</span>: protein kinase activity; protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: apoptosis; activation of caspase activity; cellular response to DNA damage stimulus; response to DNA damage stimulus; germ cell development; DNA damage response, signal transduction resulting in induction of apoptosis; DNA damage checkpoint. 11 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	476 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [NAS]
Biological Process:	germ cell development [IEP] DNA damage checkpoint [IMP] cell cycle checkpoint [ISS][TAS] apoptosis [IMP] DNA damage response, signal transduction resulting in induction of apoptosis [IMP] activation of caspase activity [IMP] protein amino acid phosphorylation [ISS][NAS] response to DNA damage stimulus [IMP]
Molecular Function:	ATP binding [IEA] protein kinase activity [ISS] protein serine/threonine kinase activity [IEA][ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARDTQGTQG TQSQASNIWT QVESQPMEKI VWGRLYGKNI KIKSLGTSSK YRIIYTHSSF  60
   61 SVDLNNDEFT AGRGEANDLI LTLNDLPEKI LTRISKVHFI IKRANCELTN PVYIQDLSRN 120
  121 GTFVNNEKIG TNRMRILKND DVISLSHPTY KAFVFKDLSP NESIGLPEEI NKTYYVNRKL 180
  181 GSGAYGLVRL VYDTRTCQQF AMKIVKKNML SGARPSTNFS DPDRVLNEAK IMKNLSHPCV 240
  241 VRMHDIVDKP DSVYMVLEFM RGGDLLNRII SNKLLSEDIS KLYFYQMCHA VKYLHDRGIT 300
  301 HRDLKPDNVL LETNDEETLL KVSDFGLSKF VQKDSVMRTL CGTPLYVAPE VLITGGREAY 360
  361 TKKVDIWSLG VVLFTCLSGT LPFSDEYGTP AAQQIKKGRF AYGHPSWKSV SQRAKLLINQ 420
  421 MLIVDPERRP SIDDVLQSSW LRDAPMLQKA KRLMKLDGME IEEENFLEPP TKRSRR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: lok-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: