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Protein Overview: FBpp0307141, CG1...

General Information:
Name(s) found: FBpp0307141 [FlyBase]
CG17331-PA / FBpp0080490 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=2L:complement(16731289..16731577,16731643..16731868,16731943..16732033); ID=FBpp0307141; name=Prosbeta4-PB; parent=FBgn0032596,FBtr0335142; dbxref=REFSEQ:NP_001260511,GB_protein:AGB93046,FlyBase:FBpp0307141,FlyBase_Annotation_IDs:CG17331-PB; MD5=bf56d4e03d9fb0b6dcff88c85f920129; length=201; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG17331 (CG17331, FBgn0032596). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16731213..16732129. It has the cytological map location 36A12. Based on sequence similarity, it is predicted to have molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus; cellular process. 3 alleles are reported. The phenotype of these alleles is annotated with: ventral furrow. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 201 amino acids

    Gene Ontology:
    Cellular Component: proteasome core complex [ISS]
    Biological Process: response to DNA damage stimulus [IMP]
    proteolysis involved in cellular protein catabolic process [IEA]
    cellular process [IMP]
    Molecular Function: endopeptidase activity [ISS]
    threonine-type endopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METLLGIKGP DFVMLAADTT HARSIIVMKE DQNKIHKVSD SLLISTVGES GDTEQFTEFI  60
   61 SKNIALYKMR NGYDLSPRES AHFTRKNLAE YLRSRTPYQV FMFVAGYDPN AGPELTFIDY 120
  121 LANALPVNYA GHGYGAIFAS SIYDRYWHPN ITQAEAYDVF KKCIAEIQKR LVVNLKNFTV 180
  181 AVVDKDGVRD LEPISAASLA A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..201] PSI-BLAST 36.39794 Proteasome beta subunit (catalytic)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • endopeptidase activity
    		•  6.91642761177919 bayes_pls_golite062009
  • peptidase activity
    		•  6.84511694091156 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  6.5973571808298 bayes_pls_golite062009
  • hydrolase activity
    		•  4.47652590304822 bayes_pls_golite062009
  • threonine-type endopeptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • threonine-type peptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009
  • binding
    		•  1.18139971903068 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.448212653390607 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle