Protein Overview: AMD_RAT

General Information:
Name(s) found:	AMD_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|URRTAP peptidylglycine monooxygenase (EC 1.14.17.3) precursor - rat [NCBI NR] gi\|2934942\|gb\|AAC05607.1\| peptidylglycine alpha-amidating monooxygenase precursor [Rattus norvegicus] [NCBI NR] gi\|206023\|gb\|AAA41803.1\| peptidyl-glycine alpha-amidating monooxygenase prepropeptide (EC 1.14.17.3) [NCBI NR] gi\|19923674\|ref\|NP_037132.2\| peptidylglycine alpha-amidating monooxygenase [Rattus norvegicus] [NCBI NR] gi\|149037430\|gb\|EDL91861.1\| peptidylglycine alpha-amidating monooxygenase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149037429\|gb\|EDL91860.1\| peptidylglycine alpha-amidating monooxygenase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149037428\|gb\|EDL91859.1\| peptidylglycine alpha-amidating monooxygenase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|113705\|sp\|P14925.1\|AMD_RAT RecName: Full=Peptidyl-glycine alpha-amidating monooxygenase; Short=PAM; Includes: RecName: Full=Peptidylglycine alpha-hydroxylating monooxygenase; Short=PHM; Includes: RecName: Full=Peptidyl-alpha-hydroxyglycine alpha-amidat [NCBI NR] Peptidyl-glycine alpha-amidating monooxygenase OS=Rattus norvegicus GN=Pam PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):9-114620759 Splice isoform PAM-1 of P14925 [hmr_yeast5_DM3-1_pombe.fasta] peptidylglycine alpha-amidating monooxygenase [HMR_022704-rand.fasta] peptidylglycine alpha-amidating monooxygenase [Rattus norvegicus]gi\|66353\|pir\|\|URRTAP peptidylglycine monooxygenase (EC 1.14.17.3) precursor - ratgi\|2934942\|gb\|AAC05607.1\| peptidylglycine alpha-amidating monooxygenase precursor [Rattus norvegicus]gi\|20 [nrdb_11152004_Chlamydomonas] (NM_013000) peptidylglycine alpha-amidating monooxygenase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (Peptidylamidoglycolate lyase) (PAL)] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] peptidylglycine alpha-amidating monooxygenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] peptidylglycine alpha-amidating monooxygenase, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] peptidylglycine alpha-amidating monooxygenase precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] peptidyl-glycine alpha-amidating monooxygenase prepropeptide (EC 1.14.17.3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Isoform PAM-1 of Peptidyl-glycine alpha-amidating monooxygenase OS=Rattus norvegicus GN=Pam [011711_HMR.fasta] Isoform of P14925, Peptidyl-glycine alpha-amidating monooxygenase OS=Rattus norvegicus GN=Pam PE=1 SV=3 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	976 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] extracellular space [IDA] transport vesicle membrane [IEA] secretory granule [IDA] membrane [IEA] integral to membrane [IEA] cytoplasmic vesicle [IEA] perikaryon [IDA]
Biological Process:	limb development [IEP] response to copper ion [IEP] lactation [IEP] response to pH [IDA] cellular process [IEA] heart development [IEP] response to hypoxia [IEP] central nervous system development [IEP] peptide metabolic process [IEA] response to drug [IDA] response to glucocorticoid stimulus [IEP] response to estradiol stimulus [IEP] oxidation reduction [IEA]
Molecular Function:	L-ascorbic acid binding [IEA] peptidylglycine monooxygenase activity [IDA][IEA] protein binding [UNKNOWN][IPI] copper ion binding [IDA][IEA] catalytic activity [IEA] metal ion binding [IEA] lyase activity [IEA] monooxygenase activity [IEA] peptidylamidoglycolate lyase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGRARSGLL LLLLGLLALQ SSCLAFRSPL SVFKRFKETT RSFSNECLGT IGPVTPLDAS  60
   61 DFALDIRMPG VTPKESDTYF CMSMRLPVDE EAFVIDFKPR ASMDTVHHML LFGCNMPSST 120
  121 GSYWFCDEGT CTDKANILYA WARNAPPTRL PKGVGFRVGG ETGSKYFVLQ VHYGDISAFR 180
  181 DNHKDCSGVS VHLTRVPQPL IAGMYLMMSV DTVIPPGEKV VNADISCQYK MYPMHVFAYR 240
  241 VHTHHLGKVV SGYRVRNGQW TLIGRQNPQL PQAFYPVEHP VDVTFGDILA ARCVFTGEGR 300
  301 TEATHIGGTS SDEMCNLYIM YYMEAKYALS FMTCTKNVAP DMFRTIPAEA NIPIPVKPDM 360
  361 VMMHGHHKEA ENKEKSALMQ QPKQGEEEVL EQGDFYSLLS KLLGEREDVH VHKYNPTEKT 420
  421 ESGSDLVAEI ANVVQKKDLG RSDAREGAEH EEWGNAILVR DRIHRFHQLE STLRPAESRA 480
  481 FSFQQPGEGP WEPEPSGDFH VEEELDWPGV YLLPGQVSGV ALDSKNNLVI FHRGDHVWDG 540
  541 NSFDSKFVYQ QRGLGPIEED TILVIDPNNA EILQSSGKNL FYLPHGLSID TDGNYWVTDV 600
  601 ALHQVFKLDP HSKEGPLLIL GRSMQPGSDQ NHFCQPTDVA VEPSTGAVFV SDGYCNSRIV 660
  661 QFSPSGKFVT QWGEESSGSS PRPGQFSVPH SLALVPHLDQ LCVADRENGR IQCFKTDTKE 720
  721 FVREIKHASF GRNVFAISYI PGFLFAVNGK PYFGDQEPVQ GFVMNFSSGE IIDVFKPVRK 780
  781 HFDMPHDIVA SEDGTVYIGD AHTNTVWKFT LTEKMEHRSV KKAGIEVQEI KEAEAVVEPK 840
  841 VENKPTSSEL QKMQEKQKLS TEPGSGVSVV LITTLLVIPV LVLLAIVMFI RWKKSRAFGD 900
  901 HDRKLESSSG RVLGRFRGKG SGGLNLGNFF ASRKGYSRKG FDRVSTEGSD QEKDEDDGTE 960
  961 SEEEYSAPLP KPAPSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: AMD_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: