Protein Overview: P85A_RAT

General Information:
Name(s) found:	P85A_RAT [Swiss-Prot]
Description(s) found: Found 18 descriptions. SHOW ALL	Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Rattus norvegicus GN=Pik3r1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	724 amino acids
Gene Ontology:
Cellular Component:	1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex [ISS] phosphoinositide 3-kinase complex [IEA][TAS] soluble fraction [IDA] cytoplasm [IEA] cytosol [UNKNOWN][IEA] protein complex [IDA] intracellular [IEA] plasma membrane [IDA]
Biological Process:	growth hormone receptor signaling pathway [UNKNOWN] response to estrogen stimulus [IPI] B cell differentiation [UNKNOWN][IEA] signal transduction [IEA] insulin receptor signaling pathway [UNKNOWN][IMP][ISS] phosphoinositide 3-kinase cascade [UNKNOWN] negative regulation of cell-cell adhesion [IMP] insulin-like growth factor receptor signaling pathway [UNKNOWN][IMP][ISS] phosphoinositide phosphorylation [ISS] response to cAMP [IDA] positive regulation of myoblast differentiation [IMP] negative regulation of proteolysis [IMP] glucose metabolic process [IMP] protein amino acid phosphorylation [UNKNOWN][IEA] aging [IEP] positive regulation of anti-apoptosis [IMP] response to insulin stimulus [IDA] negative regulation of cell-matrix adhesion [UNKNOWN][IEA] negative regulation of apoptosis [UNKNOWN][IEA] negative regulation of osteoclast differentiation [UNKNOWN][IEA] response to glucocorticoid stimulus [IDA] positive regulation of cell migration [UNKNOWN][IMP]
Molecular Function:	protein kinase binding [IPI] insulin binding [UNKNOWN] protein domain specific binding [IPI] protein phosphatase binding [UNKNOWN] phosphoinositide 3-kinase regulator activity [IEA][ISS] protein C-terminus binding [IDA] ErbB-3 class receptor binding [UNKNOWN][ISS] insulin receptor binding [UNKNOWN][ISS] receptor binding [IPI] insulin-like growth factor receptor binding [UNKNOWN][ISS] protein binding [UNKNOWN][IDA][IEA][IPI] insulin receptor substrate binding [IPI][ISS] phosphoprotein binding [IPI] 1-phosphatidylinositol-3-kinase activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAEGYQYRA LYDYKKEREE DIDLHLGDIL TVNKGSLVAL GFSDGQEARP EDIGWLNGYN  60
   61 ETTGERGDFP GTYVEYIGRK RISPPTPKPR PPRPLPVAPG SSKTEADTEQ PVLTLPDLAE 120
  121 QFAPPDVAPP LLIKLLEAIE KKGLECSTLY RTQSSSNPAE LRQLLDCDPP SVDLDVFDEH 180
  181 VLADAFKRYL ADLPNPVIPV AVYNEMMSLA QEVPSSEDYI QLLKKLIRSP NIPHQYWLTL 240
  241 QYLLKHFFKL SQASSKNLLN ARALSEIFSH VLFRFPAASS DNTEHLIKAV ELLISAEWSE 300
  301 RQPAPALPPK PPKPTSIANN SMNNNMSLQD AEWYWGDISR EEVNEKLRDT ADGTFLVRDA 360
  361 STKMHGDYTL TLRKGGNNKL IKIFHRDGKY GFSDPLTFNS VVELINHYRN ESLAQYNPKL 420
  421 DVKLLYPVSK YQQDQVVKED NIEAVGKKLH EYNTQFQEKS REYDRLYEEY TRTSQEIQMK 480
  481 RTAIEAFNDT IKIFEEQCHP QERYSKDYIE KFKREGNEKE IQRIMHNHDK LKSRISEIID 540
  541 SRRRLEEDLK KQAAEYREID KRMNSIKPDL IQLRKTRDQY LMWLTQKGVR QKKLNEWLGN 600
  601 ENTEDQYSLV DDDEDLPHHD EKTWNVGSSN RNKAENLLRG KRDGTFLVRE SSKQGCYACS 660
  661 VVVDGEVKHC VINKTATGYG FAEPYNLYSS LKELVLHYQH TSLVQHNDSL NVTLAYPVYA 720
  721 QQRR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: P85A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: