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Any process that stops, prevents or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion. Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The negative regulation of cell adhesion process by which a cell or sheet of cells splits off of an existing epithelial sheet. Any process that stops, prevents or reduces the frequency, rate, or extent of homotypic cell-cell adhesion. Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion. Any process that stops, prevents or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin. Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. The attachment of one cell to another cell via adhesion molecules. Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion. Any process that stops, prevents or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion. The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of cell-cell adhesion
Acc: GO:0022408
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.
Synonyms:
  • downregulation of cell-cell adhesion
  • down-regulation of cell-cell adhesion
  • inhibition of cell-cell adhesion
  • down regulation of cell-cell adhesion
Proteins in PDR annotated with:
   This term: 18 [Search]
   Term or descendants: 50 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0022408 - negative regulation of cell-cell adhesion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle