General Information: |
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Name(s) found: |
P85A_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 724 amino acids |
Gene Ontology: |
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Cellular Component: |
1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex
[ISS]
phosphoinositide 3-kinase complex [IEA][TAS] soluble fraction [IDA] cytoplasm [IEA] cytosol [UNKNOWN][IEA] protein complex [IDA] intracellular [IEA] plasma membrane [IDA] |
Biological Process: |
growth hormone receptor signaling pathway
[UNKNOWN]
response to estrogen stimulus [IPI] B cell differentiation [UNKNOWN][IEA] signal transduction [IEA] insulin receptor signaling pathway [UNKNOWN][IMP][ISS] phosphoinositide 3-kinase cascade [UNKNOWN] negative regulation of cell-cell adhesion [IMP] insulin-like growth factor receptor signaling pathway [UNKNOWN][IMP][ISS] phosphoinositide phosphorylation [ISS] response to cAMP [IDA] positive regulation of myoblast differentiation [IMP] negative regulation of proteolysis [IMP] glucose metabolic process [IMP] protein amino acid phosphorylation [UNKNOWN][IEA] aging [IEP] positive regulation of anti-apoptosis [IMP] response to insulin stimulus [IDA] negative regulation of cell-matrix adhesion [UNKNOWN][IEA] negative regulation of apoptosis [UNKNOWN][IEA] negative regulation of osteoclast differentiation [UNKNOWN][IEA] response to glucocorticoid stimulus [IDA] positive regulation of cell migration [UNKNOWN][IMP] |
Molecular Function: |
protein kinase binding
[IPI]
insulin binding [UNKNOWN] protein domain specific binding [IPI] protein phosphatase binding [UNKNOWN] phosphoinositide 3-kinase regulator activity [IEA][ISS] protein C-terminus binding [IDA] ErbB-3 class receptor binding [UNKNOWN][ISS] insulin receptor binding [UNKNOWN][ISS] receptor binding [IPI] insulin-like growth factor receptor binding [UNKNOWN][ISS] protein binding [UNKNOWN][IDA][IEA][IPI] insulin receptor substrate binding [IPI][ISS] phosphoprotein binding [IPI] 1-phosphatidylinositol-3-kinase activity [TAS] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSAEGYQYRA LYDYKKEREE DIDLHLGDIL TVNKGSLVAL GFSDGQEARP EDIGWLNGYN 60 61 ETTGERGDFP GTYVEYIGRK RISPPTPKPR PPRPLPVAPG SSKTEADTEQ PVLTLPDLAE 120 121 QFAPPDVAPP LLIKLLEAIE KKGLECSTLY RTQSSSNPAE LRQLLDCDPP SVDLDVFDEH 180 181 VLADAFKRYL ADLPNPVIPV AVYNEMMSLA QEVPSSEDYI QLLKKLIRSP NIPHQYWLTL 240 241 QYLLKHFFKL SQASSKNLLN ARALSEIFSH VLFRFPAASS DNTEHLIKAV ELLISAEWSE 300 301 RQPAPALPPK PPKPTSIANN SMNNNMSLQD AEWYWGDISR EEVNEKLRDT ADGTFLVRDA 360 361 STKMHGDYTL TLRKGGNNKL IKIFHRDGKY GFSDPLTFNS VVELINHYRN ESLAQYNPKL 420 421 DVKLLYPVSK YQQDQVVKED NIEAVGKKLH EYNTQFQEKS REYDRLYEEY TRTSQEIQMK 480 481 RTAIEAFNDT IKIFEEQCHP QERYSKDYIE KFKREGNEKE IQRIMHNHDK LKSRISEIID 540 541 SRRRLEEDLK KQAAEYREID KRMNSIKPDL IQLRKTRDQY LMWLTQKGVR QKKLNEWLGN 600 601 ENTEDQYSLV DDDEDLPHHD EKTWNVGSSN RNKAENLLRG KRDGTFLVRE SSKQGCYACS 660 661 VVVDGEVKHC VINKTATGYG FAEPYNLYSS LKELVLHYQH TSLVQHNDSL NVTLAYPVYA 720 721 QQRR |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)