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Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion. The binding of a cell to the extracellular matrix via adhesion molecules. Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. The attachment of a cell to the underlying substrate via adhesion molecules. Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix. Any process that stops, prevents or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. Any process that stops, prevents or reduces the rate or extent of cell adhesion to the extracellular matrix.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of cell-matrix adhesion
Acc: GO:0001953
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the rate or extent of cell adhesion to the extracellular matrix.
Synonyms:
  • down-regulation of cell-matrix adhesion
  • downregulation of cell-matrix adhesion
  • down regulation of cell-matrix adhesion
  • inhibition of cell-matrix adhesion
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 25 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001953 - negative regulation of cell-matrix adhesion (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle