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Protein Overview: CCL2_RAT

General Information:
Name(s) found: CCL2_RAT [Swiss-Prot]
Description(s) found:
Found 23 descriptions.
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  • C-C motif chemokine 2 OS=Rattus norvegicus GN=Ccl2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 148 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN][IDA]
    cytoplasm [IDA]
    neuronal cell body [IDA]
    extracellular region [UNKNOWN][IEA]
    Biological Process: response to progesterone stimulus [IEP]
    transforming growth factor beta receptor signaling pathway [IMP]
    response to amino acid stimulus [IEP]
    response to antibiotic [IEP]
    response to mechanical stimulus [IEP]
    chemotaxis [IEA]
    response to ethanol [IEP]
    inflammatory response [IEP]
    response to heat [IDA]
    response to hypoxia [IEP]
    immune response [IEA]
    anti-apoptosis [UNKNOWN][IEA]
    lymphocyte chemotaxis [IDA]
    macrophage chemotaxis [UNKNOWN][IDA]
    cytokine-mediated signaling pathway [UNKNOWN][IMP]
    response to glucocorticoid stimulus [IEP]
    response to vitamin B3 [IEP]
    response to gamma radiation [IEP]
    positive regulation of synaptic transmission [IDA]
    chemokinesis [TAS]
    maternal process involved in parturition [IEP]
    cellular calcium ion homeostasis [IDA]
    response to bacterium [UNKNOWN][IEA]
    vascular endothelial growth factor receptor signaling pathway [IMP]
    monocyte chemotaxis [UNKNOWN][IEA]
    response to drug [IEP]
    chemokine-mediated signaling pathway [IMP]
    neutrophil chemotaxis [IMP]
    response to lipopolysaccharide [IEP]
    positive regulation of endothelial cell proliferation [IMP]
    response to activity [IEP]
    organ regeneration [IEP]
    Molecular Function: G-protein-coupled receptor binding [UNKNOWN][IEA]
    protein binding [UNKNOWN][IEA]
    CCR2 chemokine receptor binding [IMP]
    heparin binding [IPI]
    chemokine activity [IDA][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVSVTLLGL LFTVAACSIH VLSQPDAVNA PLTCCYSFTG KMIPMSRLEN YKRITSSRCP  60
   61 KEAVVFVTKL KREICADPNK EWVQKYIRKL DQNQVRSETT VFYKIASTLR TSAPLNVNLT 120
  121 HKSEANASTL FSTTTSSTSV EVTSMTEN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] PSI-BLAST 19.30103 MONOCYTE CHEMOATTRACTANT PROTEIN-3, NMR, MINIMIZED AVERAGE STRUCTURE


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle