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The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Interacting selectively and non-covalently with a G-protein-coupled receptor. Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. Interacting selectively and non-covalently with any chemokine receptor. Functions to control the survival, growth, differentiation and effector function of tissues and cells. Interacting selectively with a cytokine receptor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: chemokine activity
Acc: GO:0008009
Aspect: Molecular Function
Desc: The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation.
Proteins in PDR annotated with:
   This term: 72 [Search]
   Term or descendants: 72 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008009 - chemokine activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle