Protein Overview: HMGB2_RAT

General Information:
Name(s) found:	HMGB2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393536\|ref\|NP_058883.1\| high mobility group box 2 [Rattus norvegicus] [NCBI NR] gi\|77567606\|gb\|AAI07456.1\| Hmgb2 protein [Rattus norvegicus] [NCBI NR] gi\|62662596\|ref\|XP_573903.1\| PREDICTED: high mobility group box 2 [Rattus norvegicus] [NCBI NR] gi\|62657837\|ref\|XP_573272.1\| PREDICTED: similar to High mobility group protein 2 (HMG-2) [Rattus norvegicus] [NCBI NR] gi\|58476482\|gb\|AAH89854.1\| Hmgb2 protein [Rattus norvegicus] [NCBI NR] gi\|51259308\|gb\|AAH78866.1\| Hmgb2 protein [Rattus norvegicus] [NCBI NR] gi\|1708260\|sp\|P52925.2\|HMGB2_RAT RecName: Full=High mobility group protein B2; AltName: Full=High mobility group protein 2; Short=HMG-2 [NCBI NR] gi\|149032266\|gb\|EDL87172.1\| rCG59188 [Rattus norvegicus] [NCBI NR] gi\|1304193\|dbj\|BAA12350.1\| HMG2 [Rattus norvegicus] [NCBI NR] High mobility group protein B2 OS=Rattus norvegicus GN=Hmgb2 PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):11-40070571;16-34335470 high mobility group box 2 [hmr_yeast5_DM3-1_pombe.fasta] high mobility group box 2; high mobility group protein 2 [HMR_022704-rand.fasta] Hmgb2 protein [Rattus norvegicus]gi\|1708260\|sp\|P52925\|HMG2_RAT High mobility group protein 2 (HMG-2)gi\|1304193\|dbj\|BAA12350.1\| HMG2 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hmgb2 protein [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_017187) high mobility group box 2; high mobility group protein 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] High mobility group protein B2 (High mobility group protein 2) (HMG-2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] high mobility group box 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG59188 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] HMG2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Hmgb2 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HIGH MOBILITY GROUP PROTEIN 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Hmgb2 High mobility group protein B2 [rat-ipi-250309-contam.fasta] High mobility group protein B2 OS=Rattus norvegicus GN=Hmgb2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	210 amino acids
Gene Ontology:
Cellular Component:	condensed chromosome [UNKNOWN][ISS] nucleus [UNKNOWN][IDA][ISS] extracellular space [UNKNOWN] soluble fraction [IDA] perinuclear region of cytoplasm [UNKNOWN][ISS] cytoplasm [UNKNOWN][ISS] protein complex [UNKNOWN] nucleolus [UNKNOWN] cellular_component [ND] nucleoplasm [UNKNOWN]
Biological Process:	biological_process [ND] male gonad development [UNKNOWN] spermatogenesis [UNKNOWN] positive regulation of nuclease activity [UNKNOWN] base-excision repair, DNA ligation [UNKNOWN][ISS] spermatid nucleus differentiation [UNKNOWN] nervous system development [IDA] positive regulation of megakaryocyte differentiation [UNKNOWN] positive regulation of transcription [IMP] positive regulation of DNA binding [UNKNOWN] response to steroid hormone stimulus [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] positive regulation of erythrocyte differentiation [UNKNOWN] cell cycle [IEP] regulation of transcription from RNA polymerase II promoter [UNKNOWN][ISS] cell chemotaxis [UNKNOWN] cellular response to lipopolysaccharide [UNKNOWN] negative regulation of transcription [UNKNOWN] positive regulation of DNA metabolic process [IMP] positive regulation of endothelial cell proliferation [UNKNOWN] organ regeneration [IEP] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN]
Molecular Function:	protein domain specific binding [UNKNOWN] nucleosomal histone binding [IDA] double-stranded DNA binding [TAS] DNA bending activity [UNKNOWN][ISS] chemoattractant activity [UNKNOWN] lipid binding [IDA] damaged DNA binding [UNKNOWN] molecular_function [ND] DNA binding [UNKNOWN] transcription factor activity [UNKNOWN] protein binding [UNKNOWN] promoter binding [UNKNOWN] transcription activator activity [UNKNOWN] general transcriptional repressor activity [UNKNOWN] RAGE receptor binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKGDPNKPR GKMSSYAFFV QTCREEHKKK HPDSSVNFAE FSKKCSERWK TMSAKEKSKF  60
   61 EDLAKSDKAR YDREMKNYVP PKGDKKGKKK DPNAPKRPPS AFFLFCSEHR PKIKSEHPGL 120
  121 SIGDTAKKLG EMWSEQSAKD KQPYEQKAAK LKEKYEKDIA AYRAKGKSEV GKKGPGRPTG 180
  181 SKKKNEPEDE EEEEEEEDDE DEEEEDEDEE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HMGB2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: