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Protein Overview: MK03_RAT

General Information:
Name(s) found: MK03_RAT [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • Mitogen-activated protein kinase 3 OS=Rattus norvegicus GN=Mapk3 PE=1 SV=5 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 380 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    insoluble fraction [IDA]
    microtubule cytoskeleton [UNKNOWN]
    soluble fraction [IDA]
    cytoplasm [UNKNOWN]
    cytosol [UNKNOWN][IDA]
    protein complex [IDA]
    [NOT]nucleolus [UNKNOWN]
    nucleoplasm [UNKNOWN][IDA]
    Biological Process: positive regulation of translation [IMP]
    protein complex assembly [IMP]
    small GTPase mediated signal transduction [UNKNOWN]
    positive regulation of transcription [IEP]
    intracellular protein kinase cascade [TAS]
    Ras protein signal transduction [UNKNOWN]
    protein amino acid phosphorylation [UNKNOWN][IDA][IEA][TAS]
    response to DNA damage stimulus [UNKNOWN]
    response to toxin [IDA]
    cell cycle [IEA]
    nuclear translocation of MAPK [IDA]
    organ morphogenesis [UNKNOWN]
    MAPKKK cascade [IMP]
    intracellular signaling pathway [IDA]
    response to exogenous dsRNA [UNKNOWN]
    lipopolysaccharide-mediated signaling pathway [UNKNOWN]
    response to lipopolysaccharide [UNKNOWN]
    cartilage development [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    phosphotyrosine binding [UNKNOWN]
    ATP binding [IDA][IEA]
    protein binding [UNKNOWN][IDA][IPI]
    MAP kinase activity [UNKNOWN][IDA][IEA][TAS]
    protein kinase activity [UNKNOWN]
    protein serine/threonine kinase activity [IC][UNKNOWN][IEA]
    transferase activity [IEA]
    kinase activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAAAAPGG GGGEPRGTAG VVPVVPGEVE VVKGQPFDVG PRYTQLQYIG EGAYGMVSSA  60
   61 YDHVRKTRVA IKKISPFEHQ TYCQRTLREI QILLRFRHEN VIGIRDILRA PTLEAMRDVY 120
  121 IVQDLMETDL YKLLKSQQLS NDHICYFLYQ ILRGLKYIHS ANVLHRDLKP SNLLINTTCD 180
  181 LKICDFGLAR IADPEHDHTG FLTEYVATRW YRAPEIMLNS KGYTKSIDIW SVGCILAEML 240
  241 SNRPIFPGKH YLDQLNHILG ILGSPSQEDL NCIINMKARN YLQSLPSKTK VAWAKLFPKS 300
  301 DSKALDLLDR MLTFNPNKRI TVEEALAHPY LEQYYDPTDE PVAEEPFTFD MELDDLPKER 360
  361 LKELIFQETA RFQPGAPEAP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle