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Protein Overview: APOC3_RAT

General Information:
Name(s) found: APOC3_RAT [Swiss-Prot]
Description(s) found:
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  • gi|8392912|ref|NP_036633.1| apolipoprotein C-III [Rattus norvegicus] [NCBI NR]
  • gi|6226553|sp|P06759.2|APOC3_RAT RecName: Full=Apolipoprotein C-III; Short=Apo-CIII; Short=ApoC-III; Flags: Precursor [NCBI NR]
  • gi|202940|gb|AAA40746.1| preapolipoprotein C-III [NCBI NR]
  • Apolipoprotein C-III OS=Rattus norvegicus GN=Apoc3 PE=2 SV=2 [Swiss-Prot]
  • (P06759) Apolipoprotein C-III precursor (Apo-CIII) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):None Apolipoprotein C-III precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • apolipoprotein C-III; apolipoprotein C-3 [HMR_022704-rand.fasta]
  • apolipoprotein C-III [Rattus norvegicus]gi|6226553|sp|P06759|APC3_RAT Apolipoprotein C-III precursor (Apo-CIII)gi|202940|gb|AAA40746.1| preapolipoprotein C-III [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Apolipoprotein C-III precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_012501) apolipoprotein C-3; Apolipoprotein C-III [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Apolipoprotein C-III precursor (Apo-CIII) (ApoC-III) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • apolipoprotein C-III [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • preapolipoprotein C-III [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 APOLIPOPROTEIN C-III PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Apoc3 Apolipoprotein C-III [rat-ipi-250309-contam.fasta]
  • apolipoprotein C-III precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Apolipoprotein C-III OS=Rattus norvegicus GN=Apoc3 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 101 amino acids

    Gene Ontology:
    Cellular Component: very-low-density lipoprotein particle [UNKNOWN][IEA]
    extracellular space [UNKNOWN][IDA]
    chylomicron [UNKNOWN][IEA]
    intermediate-density lipoprotein particle [UNKNOWN]
    spherical high-density lipoprotein particle [UNKNOWN]
    extracellular region [UNKNOWN][IEA]
    Biological Process: high-density lipoprotein particle remodeling [UNKNOWN]
    cholesterol metabolic process [UNKNOWN]
    triglyceride metabolic process [UNKNOWN]
    lipoprotein metabolic process [IEA]
    cholesterol homeostasis [UNKNOWN]
    negative regulation of cholesterol import [UNKNOWN]
    triglyceride mobilization [UNKNOWN]
    lipoprotein transport [IDA]
    negative regulation of very-low-density lipoprotein particle clearance [UNKNOWN]
    negative regulation of lipoprotein lipase activity [UNKNOWN]
    inflammatory response [IEP]
    negative regulation of triglyceride catabolic process [UNKNOWN]
    Cdc42 protein signal transduction [UNKNOWN]
    negative regulation of receptor-mediated endocytosis [UNKNOWN]
    triglyceride homeostasis [UNKNOWN]
    negative regulation of lipid catabolic process [UNKNOWN]
    negative regulation of fatty acid biosynthetic process [UNKNOWN]
    chylomicron remnant clearance [UNKNOWN]
    G-protein coupled receptor protein signaling pathway [UNKNOWN]
    response to nutrient [IEP]
    response to peptide hormone stimulus [IDA]
    negative regulation of lipid metabolic process [UNKNOWN]
    lipid transport [TAS]
    negative regulation of low-density lipoprotein particle clearance [UNKNOWN]
    negative regulation of very-low-density lipoprotein particle remodeling [UNKNOWN]
    response to drug [IEP]
    lipid catabolic process [IEA]
    negative regulation of high-density lipoprotein particle clearance [UNKNOWN]
    cholesterol efflux [UNKNOWN]
    triglyceride catabolic process [UNKNOWN]
    phospholipid efflux [UNKNOWN]
    Molecular Function: lipid transporter activity [TAS]
    lipase inhibitor activity [UNKNOWN]
    lipid binding [IEA]
    high-density lipoprotein receptor binding [UNKNOWN]
    phospholipid binding [UNKNOWN]
    enzyme regulator activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPRMLLIVA LVALLASARA DEGEGSLLLG SMQGYMEQAS KTVQDALSSM QESDIAVVAS  60
   61 RGWMDNRFKS LKGYWSKFTD KFTGLWESGP EDQLTTPTLE P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] Pfam 69.677781 No description for PF05778.3 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle