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Protein Overview: CO5_RAT

General Information:
Name(s) found: CO5_RAT [Swiss-Prot]
Description(s) found:
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  • gi|46397770|sp|P08650.2|CO5_RAT RecName: Full=Complement C5; Contains: RecName: Full=C5a anaphylatoxin [NCBI NR]
  • gi|1017443|emb|CAA62994.1| C5a complement component protein [Rattus norvegicus] [NCBI NR]
  • Complement C5 (Fragment) OS=Rattus norvegicus GN=C5 PE=1 SV=2 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):3-14032804 C5a complement component protein [hmr_yeast5_DM3-1_pombe.fasta]
  • C5a complement component protein [Rattus norvegicus]gi|46397770|sp|P08650|CO5_RAT Complement C5 [Contains: C5a anaphylatoxin] [nrdb_11152004_Chlamydomonas]
  • Complement C5 [Contains: C5a anaphylatoxin] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • C5a complement component protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Complement C5 (Fragment) OS=Rattus norvegicus GN=C5 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 77 amino acids

    Gene Ontology:
    Cellular Component: membrane attack complex [TAS]
    extracellular space [IDA][IEA]
    soluble fraction [IDA]
    extracellular region [UNKNOWN][IEA]
    Biological Process: cytolysis [TAS]
    tissue regeneration [IDA]
    cellular calcium ion homeostasis [IDA]
    complement activation [TAS]
    complement activation, alternative pathway [IEA]
    leukocyte migration during inflammatory response [IMP]
    inflammatory response [IDA][IEP]
    in utero embryonic development [UNKNOWN]
    induction of apoptosis [IDA]
    complement activation, classical pathway [IEA]
    glucose homeostasis [IDA]
    positive regulation of chemokine production [UNKNOWN]
    negative regulation of macrophage chemotaxis [UNKNOWN]
    positive regulation of chemotaxis [IDA]
    positive regulation vascular endothelial growth factor production [UNKNOWN]
    Molecular Function: C5a anaphylatoxin chemotactic receptor binding [IDA]
    endopeptidase inhibitor activity [IEA]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLQLLHQKVE EQAAKYKHRV PKKCCYDGAR ENKYETCEQR VARVTIGPHC IRAFNECCTI  60
   61 ADKIRKESHH KGMLLGR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77] PSI-BLAST 25.69897 No description for 2b39A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle