YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Stops, prevents or reduces the activity of an enzyme. Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process. Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity. Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: endopeptidase inhibitor activity
Acc: GO:0004866
Aspect: Molecular Function
Desc: Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
Synonyms:
  • proteinase inhibitor
  • alpha-2 macroglobulin
  • endoproteinase inhibitor
Proteins in PDR annotated with:
   This term: 85 [Search]
   Term or descendants: 625 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004866 - endopeptidase inhibitor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle