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Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. Any process of the immune system that occurs as part of an immune response. Any process that initiates an immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. An immune response mediated through a body fluid. Any process activating plasma proteins by proteolysis as part of an acute inflammatory response. Any process that stops, prevents or reduces the frequency, rate or extent of complement activation by the alternative pathway. Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway. Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: complement activation, alternative pathway
Acc: GO:0006957
Aspect: Biological Process
Desc: Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006957 - complement activation, alternative pathway (interactive image map)
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