YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any process that modulates the frequency, rate or extent of complement activation. Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein. Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. Any process that stops, prevents or reduces the frequency, rate or extent of complement activation. Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. Any process of the immune system that occurs as part of an immune response. Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis. Any process that initiates an immune response. Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. An immune response mediated through a body fluid. Any process that activates or increases the frequency, rate or extent of complement activation. Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes. Any process activating plasma proteins by proteolysis as part of an acute inflammatory response. Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: complement activation
Acc: GO:0006956
Aspect: Biological Process
Desc: Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
Synonyms:
  • complement response
  • complement activity
Proteins in PDR annotated with:
   This term: 41 [Search]
   Term or descendants: 92 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006956 - complement activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle