Protein Overview: GCR_RAT

General Information:
Name(s) found:	GCR_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|1169883\|sp\|P06536.2\|GCR_RAT RecName: Full=Glucocorticoid receptor; Short=GR; AltName: Full=Nuclear receptor subfamily 3 group C member 1 [NCBI NR] Glucocorticoid receptor OS=Rattus norvegicus GN=Nr3c1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):18-53280771;18-53280771 Glucocorticoid receptor [hmr_yeast5_DM3-1_pombe.fasta] Glucocorticoid receptor (GR) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Glucocorticoid receptor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 GLUCOCORTICOID RECEPTOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Nr3c1 Isoform A of Glucocorticoid receptor [rat-ipi-250309-contam.fasta] Isoform A of Glucocorticoid receptor OS=Rattus norvegicus GN=Nr3c1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	795 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA][TAS] cytoplasm [UNKNOWN][IMP] membrane [UNKNOWN] cytosol [UNKNOWN] protein complex [IDA] [NOT]nucleolus [UNKNOWN] intracellular [UNKNOWN]
Biological Process:	glucocorticoid receptor signaling pathway [UNKNOWN] regulation of transcription, DNA-dependent [UNKNOWN][IMP] transcription from RNA polymerase II promoter [IDA] mammary gland duct morphogenesis [UNKNOWN] regulation of gluconeogenesis [UNKNOWN] glucocorticoid metabolic process [UNKNOWN] regulation of cell proliferation [IDA] positive regulation of neuron apoptosis [UNKNOWN] regulation of glucocorticoid biosynthetic process [UNKNOWN] chromatin remodeling [IMP] anti-apoptosis [IMP] response to arsenic [IMP] chromatin-mediated maintenance of transcription [IMP] response to protein stimulus [UNKNOWN] adrenal gland development [UNKNOWN] negative regulation of transforming growth factor beta receptor signaling pathway [IMP]
Molecular Function:	heat shock protein binding [IDA] zinc ion binding [TAS] identical protein binding [IPI] protein homodimerization activity [IDA] double-stranded DNA binding [IDA] sequence-specific DNA binding [UNKNOWN][IDA] protein dimerization activity [UNKNOWN][TAS] chromatin binding [IPI] steroid binding [IDA] glucocorticoid receptor activity [UNKNOWN][IMP] NF-kappaB binding [IPI] DNA binding [UNKNOWN][IDA] transcription factor activity [IMP] protein binding [UNKNOWN][IPI] transcription regulator activity [UNKNOWN] metal ion binding [IEA] protein heterodimerization activity [IDA] transcription activator activity [IDA][IMP] protein complex binding [IPI] receptor tyrosine kinase binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSKESLAPP GRDEVPGSLL GQGRGSVMDF YKSLRGGATV KVSASSPSVA AASQADSKQQ  60
   61 RILLDFSKGS TSNVQQRQQQ QQQQQQQQQQ QQQQQQPDLS KAVSLSMGLY MGETETKVMG 120
  121 NDLGYPQQGQ LGLSSGETDF RLLEESIANL NRSTSVPENP KSSTSATGCA TPTEKEFPKT 180
  181 HSDASSEQQN RKSQTGTNGG SVKLYPTDQS TFDLLKDLEF SAGSPSKDTN ESPWRSDLLI 240
  241 DENLLSPLAG EDDPFLLEGN TNEDCKPLIL PDTKPKIKDT GDTILSSPSS VALPQVKTEK 300
  301 DDFIELCTPG VIKQEKLGPV YCQASFSGTN IIGNKMSAIS VHGVSTSGGQ MYHYDMNTAS 360
  361 LSQQQDQKPV FNVIPPIPVG SENWNRCQGS GEDSLTSLGA LNFPGRSVFS NGYSSPGMRP 420
  421 DVSSPPSSSS AATGPPPKLC LVCSDEASGC HYGVLTCGSC KVFFKRAVEG QHNYLCAGRN 480
  481 DCIIDKIRRK NCPACRYRKC LQAGMNLEAR KTKKKIKGIQ QATAGVSQDT SENPNKTIVP 540
  541 AALPQLTPTL VSLLEVIEPE VLYAGYDSSV PDSAWRIMTT LNMLGGRQVI AAVKWAKAIL 600
  601 GLRNLHLDDQ MTLLQYSWMF LMAFALGWRS YRQSSGNLLC FAPDLIINEQ RMSLPCMYDQ 660
  661 CKHMLFVSSE LQRLQVSYEE YLCMKTLLLL SSVPKEGLKS QELFDEIRMT YIKELGKAIV 720
  721 KREGNSSQNW QRFYQLTKLL DSMHEVVENL LTYCFQTFLD KTMSIEFPEM LAEIITNQIP 780
  781 KYSNGNIKKL LFHQK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.78

Protein Overview: GCR_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: