Protein Overview: CP3A1_RAT

General Information:
Name(s) found:	CP3A1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A22631 cytochrome P450 3A1, pregnenolone 16-alpha-carbonitrile-inducible - rat [NCBI NR] gi\|27465619\|ref\|NP_775167.1\| cytochrome P450, family 3, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|203778\|gb\|AAA41035.1\| Cytochrome P-450PCN [NCBI NR] gi\|117153\|sp\|P04800.1\|CP3A1_RAT RecName: Full=Cytochrome P450 3A1; AltName: Full=CYPIIIA1; AltName: Full=P450-PCN1 [NCBI NR] Cytochrome P450 3A1 OS=Rattus norvegicus GN=Cyp3a1 PE=1 SV=1 [Swiss-Prot] (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1) [Swiss-Prot] Ensembl_locations(Chr-bp):None Cytochrome P450 3A1 [hmr_yeast5_DM3-1_pombe.fasta] cytochrome P-450PCN (PNCN inducible) [HMR_022704-rand.fasta] cytochrome P-450PCN (PNCN inducible) [Rattus norvegicus]gi\|117153\|sp\|P04800\|CP31_RAT Cytochrome P450 3A1 (CYPIIIA1) (P450-PCN1)gi\|92166\|pir\|\|A22631 cytochrome P450 3A1, pregnenolone 16-alpha-carbonitrile-inducible - ratgi\|203778\|gb\|AAA41035.1\| Cytochro [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Cytochrome P450 3A1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Cytochrome P450 3A1 (CYPIIIA1) (P450-PCN1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Cytochrome P-450PCN [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CYTOCHROME P450 3A1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] cytochrome P-450PCN (PNCN inducible) [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Cyp3a23/3a1 Cytochrome P450 3A1 [rat-ipi-250309-contam.fasta] Cytochrome P450 3A1 OS=Rattus norvegicus GN=Cyp3a1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	504 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [UNKNOWN][IMP] cytoplasm [UNKNOWN] membrane [IEA] microsome [UNKNOWN][IDA] endoplasmic reticulum [IEA] cell surface [UNKNOWN]
Biological Process:	drug catabolic process [UNKNOWN] exogenous drug catabolic process [UNKNOWN] steroid metabolic process [UNKNOWN] response to nutrient [IEP] response to cadmium ion [IEP] aging [IEP] alkaloid catabolic process [UNKNOWN] heterocycle metabolic process [UNKNOWN] response to drug [IEP] steroid catabolic process [UNKNOWN] response to glucocorticoid stimulus [IEP] monoterpenoid metabolic process [UNKNOWN] response to metal ion [IEP] drug metabolic process [UNKNOWN] oxidation reduction [UNKNOWN][IEA] oxidative demethylation [UNKNOWN]
Molecular Function:	oxygen binding [UNKNOWN] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [IEA] demethylase activity [IDA] steroid hydroxylase activity [UNKNOWN] electron carrier activity [IEA] steroid binding [UNKNOWN] monooxygenase activity [UNKNOWN] heme binding [IEA] iron ion binding [UNKNOWN] oxidoreductase activity [UNKNOWN] metal ion binding [IEA] aromatase activity [IEA] caffeine oxidase activity [UNKNOWN] testosterone 6-beta-hydroxylase activity [UNKNOWN][IDA] vitamin D3 25-hydroxylase activity [UNKNOWN] vitamin D 24-hydroxylase activity [UNKNOWN] enzyme binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLLSALTLE TWVLLAVVLV LLYGFGTRTH GLFKKQGIPG PKPLPFFGTV LNYYMGLWKF  60
   61 DVECHKKYGK IWGLFDGQMP LFAITDTEMI KNVLVKECFS VFTNRRDFGP VGIMGKAVSV 120
  121 AKDEEWKRYR ALLSPTFTSG RLKEMFPIIE QYGDILVKYL KQEAETGKPV TMKKVFGAYS 180
  181 MDVITSTSFG VNVDSLNNPK DPFVEKTKKL LRFDFFDPLF LSVVLFPFLT PIYEMLNICM 240
  241 FPKDSIEFFK KFVYRMKETR LDSVQKHRVD FLQLMMNAHN DSKDKESHTA LSDMEITAQS 300
  301 IIFIFAGYEP TSSTLSFVLH SLATHPDTQK KLQEEIDRAL PNKAPPTYDT VMEMEYLDMV 360
  361 LNETLRLYPI GNRLERVCKK DVEINGVFMP KGSVVMIPSY ALHRDPQHWP EPEEFRPERF 420
  421 SKENKGSIDP YVYLPFGNGP RNCIGMRFAL MNMKLALTKV LQNFSFQPCK ETQIPLKLSR 480
  481 QGLLQPTKPI ILKVVPRDEI ITGS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CP3A1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: