Protein Overview: APBB1_RAT

General Information:
Name(s) found:	APBB1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|52788204\|sp\|P46933.3\|APBB1_RAT RecName: Full=Amyloid beta A4 precursor protein-binding family B member 1; AltName: Full=Protein Fe65 [NCBI NR] gi\|17978453\|ref\|NP_536726.1\| amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) [Rattus norvegicus] [NCBI NR] gi\|13377732\|gb\|AAK20835.1\| FE65 [Rattus norvegicus] [NCBI NR] Amyloid beta A4 precursor protein-binding family B member 1 OS=Rattus norvegicus GN=Apbb1 PE=1 SV=3 [Swiss-Prot] (P46933) Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein) [Swiss-Prot] Ensembl_locations(Chr-bp):1-167713741 FE65 [hmr_yeast5_DM3-1_pombe.fasta] amyloid beta (A4) precursor protein-binding, family B, member 1 [HMR_022704-rand.fasta] amyloid beta (A4) precursor protein-binding, family B, member 1 [Rattus norvegicus]gi\|13377732\|gb\|AAK20835.1\| FE65 [Rattus norvegicus]gi\|52788204\|sp\|P46933\|ABB1_RAT Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein) [nrdb_11152004_Chlamydomonas] (NM_080478) amyloid beta (A4) precursor protein-binding, family B, member 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 1 of Amyloid beta A4 precursor protein-binding family B member 1 [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] amyloid beta (A4) precursor protein-binding, family B, member 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] FE65 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] amyloid beta A4 precursor protein-binding family B member 1 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform 1 of Amyloid beta A4 precursor protein-binding family B member 1 OS=Rattus norvegicus GN=Apbb1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	711 amino acids
Gene Ontology:
Cellular Component:	growth cone [UNKNOWN][ISS] presynaptic membrane [IDA] nucleus [UNKNOWN][IDA][ISS] perinuclear region of cytoplasm [IDA] cytoplasm [UNKNOWN][IDA] postsynaptic membrane [IDA] dendritic spine [IDA] protein complex [IDA] synapse [UNKNOWN][ISS] plasma membrane [UNKNOWN][IEA] lamellipodium [UNKNOWN][ISS]
Biological Process:	cell cycle arrest [ISS] chromatin modification [IEA] histone H4 acetylation [IMP] positive regulation of DNA repair [IMP] negative regulation of S phase of mitotic cell cycle [ISS] axon guidance [UNKNOWN][IEA] visual learning [UNKNOWN][IEA] response to DNA damage stimulus [UNKNOWN][IEA] regulation of transcription [ISS] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] double-strand break repair [IMP] neuron migration [UNKNOWN][IEA] negative regulation of thymidylate synthase biosynthetic process [ISS] negative regulation of cell growth [ISS] positive regulation of transcription, DNA-dependent [IDA] positive regulation of apoptosis [UNKNOWN][ISS] response to iron ion [IEP] extracellular matrix organization [UNKNOWN][IEA] positive regulation of protein secretion [IMP]
Molecular Function:	proline-rich region binding [UNKNOWN] protein binding [UNKNOWN][IPI] histone binding [UNKNOWN] transcription factor binding [ISS] protein complex binding [IPI] beta-amyloid binding [UNKNOWN][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVPSSLSQS AINANSHGGP ALSFPFPLHA AHNQLLNAKL QATAVVPKDL RSAMGEGSVP  60
   61 EPGPANAKWL KEGQNQLRRA ATAHRDQNRN VTLTLAEEAS QEAETAPLGP KGLMHLYSEL 120
  121 ELSAHNAANR GLHGSALIIN TQGLGPDEGE EKAAGEVEEE DEDEEEEDEE EEDLSSPQGL 180
  181 PEPLENVEVP SGPQVLTDGP REHSKSASLL FGMRNSAASD EDSSWATLSQ GSPSYGSPED 240
  241 TDSFWNPNAF ETDSDLPAGW MRVQDTSGTY YWHIPTGTTQ WEPPGRASPS QGNSPQEESQ 300
  301 LTWTGFAHQE GFEEGEFWKD EPSEEAPMEL GLKDPEEGTL PFSAQSLSPE PVPQEEENLP 360
  361 QRNANPGIKC FAVRSLGWVE MTEEELAPGR SSVAVNNCIR QLSYHKNNLH DPMSGGWGEG 420
  421 KDLLLQLEDE TLKLVEPQNQ TLLHAQPIVS IRVWGVGRDS GRERDFAYVA RDKLTQMLKC 480
  481 HVFRCEAPAK NIATSLHEIC SKIMSERRNA RCLVNGLSLD HSKLVDVPFQ VEFPAPKNEL 540
  541 VQKFQVYYLG NVPVAKPVGV DVINGALESV LSSSSREQWT PSHVSVAPAT LTILHQQTEA 600
  601 VLGECRVRFL SFLAVGRDVH TFAFIMAAGP ASFCCHMFWC EPNAASLSEA VQAACMLRYQ 660
  661 KCLDARSQTS TSCLPAPPAE SVARRVGWTV RRGVQSLWGS LKPKRLGSQT P

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.49

Protein Overview: APBB1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: