Protein Overview: CDK1_RAT

General Information:
Name(s) found:	CDK1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9506475\|ref\|NP_062169.1\| cell division cycle 2 [Rattus norvegicus] [NCBI NR] gi\|729074\|sp\|P39951.1\|CDC2_RAT RecName: Full=Cell division control protein 2 homolog; AltName: Full=p34 protein kinase; AltName: Full=Cyclin-dependent kinase 1; Short=CDK1 [NCBI NR] gi\|60552259\|gb\|AAH91549.1\| Cdc2 protein [Rattus norvegicus] [NCBI NR] gi\|57534\|emb\|CAA43177.1\| cdc2(+) [Rattus norvegicus] [NCBI NR] gi\|149043847\|gb\|EDL97298.1\| cell division cycle 2 homolog A (S. pombe) [Rattus norvegicus] [NCBI NR] pir\|\|S24913 protein kinase (EC 2.7.1.37) cdc2 [similarity] - rat [NCBI NR] Cyclin-dependent kinase 1 OS=Rattus norvegicus GN=Cdk1 PE=1 SV=1 [Swiss-Prot] Cell division control protein 2 homolog OS=Rattus norvegicus GN=Cdc2 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):20-20151596 Cell division control protein 2 homolog [hmr_yeast5_DM3-1_pombe.fasta] cell division cycle 2 homolog A; Cell division cycle control protein 2 [HMR_022704-rand.fasta] cell division cycle 2 homolog A [Rattus norvegicus]gi\|57534\|emb\|CAA43177.1\| cdc2(+) [Rattus norvegicus]gi\|729074\|sp\|P39951\|CDC2_RAT Cell division control protein 2 homolog (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1)gi\|111499\|pir\|\|S24913 pro [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Cell division control protein 2 homolog [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_019296) Cell division cycle control protein 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Ensembl_locations(Chr-bp):20-20151596 Cell division control protein 2 homolog [EBI-IPI_Drosophila_na_12-13-2007_con_reversed.fasta] Cell division control protein 2 homolog (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cell division cycle 2 homolog A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cell division cycle 2 homolog A (S. pombe) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cdc2(+) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Cdc2a protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CELL DIVISION CONTROL PROTEIN 2 HOMOLOG [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] cell division cycle 2 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Cdc2 Cell division control protein 2 homolog [rat-ipi-250309-contam.fasta] Cell division protein kinase 1 OS=Rattus norvegicus GN=Cdk1 [011711_HMR.fasta] Cyclin-dependent kinase 1 OS=Rattus norvegicus GN=Cdk1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta] Cyclin-dependent kinase 1 OS=Rattus norvegicus GN=Cdk1 [120808_122_R_norvegicus.fasta]
Organism:	Rattus norvegicus
Length:	297 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] spindle microtubule [UNKNOWN] cytoplasm [IDA] cytosol [UNKNOWN] midbody [UNKNOWN] nucleoplasm [UNKNOWN]
Biological Process:	mitotic cell cycle G2/M transition DNA damage checkpoint [UNKNOWN][IEA] positive regulation of cardiac muscle cell proliferation [IMP] positive regulation of protein import into nucleus, translocation [IMP] protein complex assembly [IDA] positive regulation of DNA replication [IMP] response to axon injury [IEP] protein amino acid phosphorylation [UNKNOWN][IEA] response to toxin [IEP] mitotic cell cycle [IEP] cell division [IEA] response to ethanol [IDA] anti-apoptosis [UNKNOWN] protein localization to kinetochore [UNKNOWN] G1 phase of mitotic cell cycle [TAS] cellular response to hydrogen peroxide [IEP] response to amine stimulus [IEP] chromosome condensation [IMP] response to copper ion [IEP] mitosis [IEA] response to cadmium ion [IEP] response to organic cyclic substance [IEP] response to hydrogen peroxide [IEP] cell aging [IDA] positive regulation of mitotic cell cycle [IMP] positive regulation of gene expression [IMP] response to drug [IEP] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [UNKNOWN] ventricular cardiac muscle cell development [IEP] response to activity [IEP] organ regeneration [IMP] cellular response to protein stimulus [IEP] positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [UNKNOWN] response to organic nitrogen [IDA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein binding [UNKNOWN] RNA polymerase II carboxy-terminal domain kinase activity [UNKNOWN][IEA] histone kinase activity [IDA] cyclin binding [IPI] cyclin-dependent protein kinase activity [UNKNOWN][IEA] transferase activity [IEA] kinase activity [UNKNOWN] Hsp70 protein binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDYIKIEKI GEGTYGVVYK GRHRTTGQIV AMKKIRLESE EEGVPSTAIR EISLLKELRH  60
   61 PNIVSLQDVL MQDSRLYLIF EFLSMDLKKY LDSIPPGQFM DSSLVKSYLY QILQGIVFCH 120
  121 SRRVLHRDLK PQNLLIDDKG TIKLADFGLA RAFGIPIRVY THEVVTLWYR SPEVLLGSAR 180
  181 YSTPVDIWSI GTIFAELATK KPLFHGDSEI DQLFRIFRAL GTPNNEVWPE VESLQDYKNT 240
  241 FPKWKPGSLA SHVKNLDENG LDLLSKMLVY DPAKRISGKM ALKHPYFDDL DNQIKKM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: CDK1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: