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Protein Overview: CDK1_RAT

General Information:
Name(s) found: CDK1_RAT [Swiss-Prot]
Description(s) found:
Found 25 descriptions.
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  • Cyclin-dependent kinase 1 OS=Rattus norvegicus GN=Cdk1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 297 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    spindle microtubule [UNKNOWN]
    cytoplasm [IDA]
    cytosol [UNKNOWN]
    midbody [UNKNOWN]
    nucleoplasm [UNKNOWN]
    Biological Process: mitotic cell cycle G2/M transition DNA damage checkpoint [UNKNOWN][IEA]
    positive regulation of cardiac muscle cell proliferation [IMP]
    positive regulation of protein import into nucleus, translocation [IMP]
    protein complex assembly [IDA]
    positive regulation of DNA replication [IMP]
    response to axon injury [IEP]
    protein amino acid phosphorylation [UNKNOWN][IEA]
    response to toxin [IEP]
    mitotic cell cycle [IEP]
    cell division [IEA]
    response to ethanol [IDA]
    anti-apoptosis [UNKNOWN]
    protein localization to kinetochore [UNKNOWN]
    G1 phase of mitotic cell cycle [TAS]
    cellular response to hydrogen peroxide [IEP]
    response to amine stimulus [IEP]
    chromosome condensation [IMP]
    response to copper ion [IEP]
    mitosis [IEA]
    response to cadmium ion [IEP]
    response to organic cyclic substance [IEP]
    response to hydrogen peroxide [IEP]
    cell aging [IDA]
    positive regulation of mitotic cell cycle [IMP]
    positive regulation of gene expression [IMP]
    response to drug [IEP]
    anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [UNKNOWN]
    ventricular cardiac muscle cell development [IEP]
    response to activity [IEP]
    organ regeneration [IMP]
    cellular response to protein stimulus [IEP]
    positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [UNKNOWN]
    response to organic nitrogen [IDA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    protein binding [UNKNOWN]
    RNA polymerase II carboxy-terminal domain kinase activity [UNKNOWN][IEA]
    histone kinase activity [IDA]
    cyclin binding [IPI]
    cyclin-dependent protein kinase activity [UNKNOWN][IEA]
    transferase activity [IEA]
    kinase activity [UNKNOWN]
    Hsp70 protein binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDYIKIEKI GEGTYGVVYK GRHRTTGQIV AMKKIRLESE EEGVPSTAIR EISLLKELRH  60
   61 PNIVSLQDVL MQDSRLYLIF EFLSMDLKKY LDSIPPGQFM DSSLVKSYLY QILQGIVFCH 120
  121 SRRVLHRDLK PQNLLIDDKG TIKLADFGLA RAFGIPIRVY THEVVTLWYR SPEVLLGSAR 180
  181 YSTPVDIWSI GTIFAELATK KPLFHGDSEI DQLFRIFRAL GTPNNEVWPE VESLQDYKNT 240
  241 FPKWKPGSLA SHVKNLDENG LDLLSKMLVY DPAKRISGKM ALKHPYFDDL DNQIKKM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle