Protein Overview: NR0B1_RAT

General Information:
Name(s) found:	NR0B1_RAT [Swiss-Prot]
Description(s) found: Found 17 descriptions. SHOW ALL	Nuclear receptor subfamily 0 group B member 1 OS=Rattus norvegicus GN=Nr0b1 PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	472 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IEA] nucleus [UNKNOWN][IDA][ISS] cytoplasm [UNKNOWN][IDA] polysomal ribosome [UNKNOWN][ISS]
Biological Process:	response to organic substance [IEP] male gonad development [UNKNOWN] negative regulation of steroid hormone receptor signaling pathway [UNKNOWN][IEA] spermatogenesis [UNKNOWN][IEP] protein localization [UNKNOWN][IEA] Sertoli cell differentiation [UNKNOWN][IEA] negative regulation of transcription factor activity [UNKNOWN][IMP] steroid biosynthetic process [UNKNOWN][ISS] sex determination [UNKNOWN] response to peptide hormone stimulus [IEP] response to stress [UNKNOWN][IEA] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IMP] male sex determination [UNKNOWN][IEA] gonad development [UNKNOWN][ISS] negative regulation of transcription, DNA-dependent [UNKNOWN][ISS] negative regulation of cell differentiation [UNKNOWN][IEA] negative regulation of transcription [UNKNOWN][ISS] cell differentiation [UNKNOWN] regulation of steroid biosynthetic process [TAS] Leydig cell differentiation [UNKNOWN][IEA] adrenal gland development [UNKNOWN][ISS]
Molecular Function:	protein domain specific binding [UNKNOWN][IEA] protein homodimerization activity [UNKNOWN][IEA] double-stranded DNA binding [IMP] sequence-specific DNA binding [UNKNOWN][IMP][ISS] transcription factor binding [UNKNOWN][IEA] DNA binding [UNKNOWN][ISS][TAS] transcription factor activity [IEA] RNA binding [UNKNOWN][ISS] protein binding [UNKNOWN] transcription corepressor activity [UNKNOWN][IEA] AF-2 domain binding [UNKNOWN] basal transcription repressor activity [UNKNOWN][ISS] ligand-regulated transcription factor activity [UNKNOWN][ISS] steroid hormone receptor activity [IEA] transcription repressor activity [UNKNOWN][IMP][TAS] DNA hairpin binding [UNKNOWN][ISS] steroid hormone receptor binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGEDHPWHG SILYNLLMSA KQKHGSREER EVRLGAQCWG CACGTQPVLG GEGLPGGQAL  60
   61 SLLYRCCFCG ENHPRQGGIL YSMLTNARQP SGATEAPRAR FRTPCWGCAC SNAKPLVGRX 120
  121 GLPAGQVPSL LYRCCFCGKK HPRQGSILYS LLTNAQQTHV SREVPEAHRG GEWWQLSYCT 180
  181 HNVGGPEGLQ STQAMAFLYR SYVCCEEQPQ QSSVASDTPV RADQTPAAPQ EQPRAPWWDT 240
  241 SSGVQRPIAL KDPQVVCEAA SAGLLKTLRF VKYLPCFQIL PLDQQLVLVR SCWAPLLMLE 300
  301 LAQDHLHFEM MEISEPNLMH EMLTTRRQET EGPEPADPQA TEQPQTVSAE AGHVLSVAAV 360
  361 QAIKSFFFKC WSLNIDTKEY AYLKGTVLFN PDLPGLQCVK YIESLQWRTQ QILTEHIRLM 420
  421 QREYQIRSAE LNSALFLLRF INTDVVTELF FRPIIGAVSM DDMMLEMLCA KL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: NR0B1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: