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Protein Overview: MK14_RAT

General Information:
Name(s) found: MK14_RAT [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Mitogen-activated protein kinase 14 OS=Rattus norvegicus GN=Mapk14 PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 360 amino acids

    Gene Ontology:
    Cellular Component: cell [UNKNOWN][IEA]
    nucleus [IDA][ISS]
    soluble fraction [IDA]
    cytoplasm [ISS]
    spindle pole [UNKNOWN][IEA]
    cytosol [UNKNOWN][IDA]
    cytosolic part [IDA]
    nucleoplasm [UNKNOWN]
    Biological Process: response to muramyl dipeptide [UNKNOWN][IEA]
    cell morphogenesis [UNKNOWN][IEA]
    chondrocyte differentiation [UNKNOWN][IEA]
    protein amino acid autophosphorylation [IDA]
    intracellular protein kinase cascade [UNKNOWN][ISS][TAS]
    Ras protein signal transduction [UNKNOWN]
    glucose metabolic process [UNKNOWN][IEA]
    protein amino acid phosphorylation [UNKNOWN][IDA][IEA][TAS]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    positive regulation of erythrocyte differentiation [UNKNOWN][IEA]
    response to stress [UNKNOWN][ISS]
    DNA damage checkpoint [UNKNOWN][IEA]
    response to glucose stimulus [IEP]
    fatty acid oxidation [UNKNOWN][IEA]
    angiogenesis [UNKNOWN][IEA]
    skeletal muscle tissue development [UNKNOWN][IEA]
    lipopolysaccharide-mediated signaling pathway [UNKNOWN][IEA]
    response to lipopolysaccharide [UNKNOWN][IEA]
    stress-activated MAPK cascade [IDA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IDA][IEA]
    protein binding [UNKNOWN]
    protein C-terminus binding [IDA]
    MAP kinase activity [UNKNOWN][IDA][IEA][TAS]
    protein kinase activity [UNKNOWN][IEA]
    protein serine/threonine kinase activity [UNKNOWN][IEA]
    MP kinase activity [UNKNOWN][ISS]
    transferase activity [IEA]
    kinase activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQERPTFYR QELNKTVWEV PERYQNLSPV GSGAYGSVCA AFDTKTGHRV AVKKLSRPFQ  60
   61 SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ 120
  121 KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT 180
  181 GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHID QLKLILRLVG 240
  241 TPGAELLKKI SSESARNYIQ SLAQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA 300
  301 QALAHAYFAQ YHDPDDEPVA EPYDQSFESR DFLIDEWKSL TYDEVISFVP PPLDQEEMES 360
  361

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle