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Protein Overview: UCK2_MOUSE

General Information:
Name(s) found: UCK2_MOUSE [Swiss-Prot]
Description(s) found:
Found 32 descriptions.
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  • Uridine-cytidine kinase 2 OS=Mus musculus GN=Uck2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: microsome [UNKNOWN]
    cytosol [UNKNOWN]
    cellular_component [ND]
    Biological Process: biological_process [ND]
    metabolic process [IEA]
    auxin biosynthetic process [IEA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    uridine kinase activity [IEA]
    transferase activity [IEA]
    phosphotransferase activity, alcohol group as acceptor [IEA]
    kinase activity [IEA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGDSEQTLQ NHQQPNGGEP FLIGVSGGTA SGKSSVCAKI VQLLGQNEVD YHQKQVVILS  60
   61 QDSFYRVLTS EQKAKALKGQ FNFDHPDAFD NELIFKTLKE ITEGKTVQIP VYDFVSHSRK 120
  121 EETVTIYPAD VVLFEGILAF YSQEVRDLFQ MKLFVDTDAD TRLSRRVLRD ISERGRDLEQ 180
  181 ILSQYITFVK PAFEEFCLPT KKYADVIIPR GADNLVAINL IVQHIQDILN GGLSKRQTNG 240
  241 YLNGYTPSRK RQASESSSRP H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..261] PSI-BLAST 73.522879 Rapid structure determination of human uridine-cytidine kinase 2 using a conventional laboratory X-ray source and a single samarium derivative

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.66392587433723 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.28726855139279 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  2.24094813695083 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.23754609668547 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.21702600128327 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.21503003850174 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.96697952975573 bayes_pls_golite062009
  • binding
    		•  1.8576045268999 bayes_pls_golite062009
  • transporter activity
    		•  1.85044926113762 bayes_pls_golite062009
  • ATPase activity
    		•  1.70670922135201 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.656935231793 bayes_pls_golite062009
  • hydrolase activity
    		•  1.20846280768115 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.02588328213159 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ATP binding
    		•  0.98146619596929 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.949788783884952 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.931486373329219 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • GTPase activity
    		•  0.768815888267067 bayes_pls_golite062009
  • kinase activity
    		•  0.691112783105676 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.499834566483656 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.464456497491373 bayes_pls_golite062009
  • adenylate kinase activity
    		•  0.447752711852745 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.390479076640045 bayes_pls_golite062009
  • protein binding
    		•  0.378225828131122 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.226172885205141 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.216266069700019 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.0756212238097211 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0430764033739892 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle